Featured Structures

ChemDiv has developed successful new approaches to high-yield syntheses of small libraries (up to 100 members) of Podophyllotoxin derivatives based on lactone ring cleavage with primary and secondary amines. Podophyllotoxin-like Compounds enabled by our novel synthetic approaches will soon be included in our new Natural-Like Compounds, PPI-modulators, anti-viral and other focused libraries.

The scaffold CM3990 is an example of our newest alpha-helix mimetics libraries. The strategy of design of helix-mimetics is described in the adjacent panel.