Publications in 2008

  1. Alyabyev S. B.; Kravchenko D. B.; Dorogov M. V.; Ivachtchenko A. V. Synthesis tional 4-substituted-amino-5,6-dimetilfuro [2,3-d] pyrimidine-2-carboxylic acid. Proceedings of the Universities, Chemistry and Chemical Engineering. Technology, 2008, 51(2), 3–5.

  2. Alyabyev S. B.; Kravchenko D. B.; Dorogov M. V.; Ivachtchenko A. V. Universal approach to the synthesis of libraries of substituted isoxazolo [5,4-d] pyrimidine. Proceedings of the Universities, Chemistry and Chemical Engineering. Technology, 2008, 51(2), 10–18.

  3. Sakharov V. N.; Kalandadze L. S.; Khristolyubova T. A.; Smirnov A. B.; Plahtinsky V. V.; Ivachtchenko A. V. A study of denitrocyclization in the synthesis of dibenzoxyazepinones and dibenzotioazepinones. Proceedings of the Universities, Chemistry and Chemical Engineering. Technology, 2008, 51(9), 73–75.

  4. Sapegin, A. V.; Sakharov V. N.; Khristolyubova T. A.; Smirnov A. B.; Dorogov M. V.; Ivachtchenko A. V. Using an intramolecular nucleophilic aromatic substitution reaction in the synthesis of benzoxy azepinone systems. Proceedings of the Universities, Chemistry and Chemical Engineering. Technology, 2008, 51(10), 62–64.

  5. Kysil V. M.; Balakin K. V.; Tkachenko S. E.; Ivachtchenko A. V. Caspase activity modulators as anticancer agents. Anti-Cancer Agents Med. Chem., 2008, 8(3), 322–341.

  6. Alyabiev S. B.; Kravchenko D. V.; Ivachtchenko A. V. Regioselective synthesis of substituted isoxazolo[5,4-d]pyrimidines. Mend. Commun., 2008, 18(3), 144–146.

  7. Alyabiev S. B.; Kravchenko D. V.; Ivachtchenko A. V. Synthesis of ethyl 4-oxo-3,4-dihydro[1]benzofuro[3,2-d]pyrimidine-2-carboxylate and its derivatives. Mend. Commun., 2008, 18(4), 217–219.

  8. Sapegin A. V.; Sakharov V. N.; Kalandadze L. S.; Smirnov A. V.; Khristolyubova T. A.; Plahtinsky V. V.; Ivachtchenko A. V. Synthesis of dibenzo[b,f][1,4]oxazepin-11(10H)-one and pyrido[2,3-b][1,4]benzoxazepin-10(11H)-one compounds based on o-nitrochloro derivatives of benzene and pyridine. Mend. Commun., 2008, 18(5), 281–283.

  9. Sandulenko Yu. B.; Ivachtchenko A. V.; Kravchenko D. V.; Tkachenko S. E.; Vvedensky V. Yu. Parallel solid-phase synthesis of novel 3,7-diazabicyclo[3.3.1]nonane derivatives starting from natural alkaloid cytisine. Russ. Chem. Bull., 2008, 57(9), 1999–2004.

  10. Lavrovsky Y.; Ivanenkov Y. A.; Balakin K. V.; Medvedeva D. A.; Ivachtchenko A. V. CXCR4 receptor as a promising target for oncolytic drugs. Mini Reviews in Med. Chem., 2008, 8(11), 1075–1087.

  11. Krasavin M.; Tsirulnikov S.; Nikulnikov M.; Kysil V.; Ivachtchenko A. Poorly reactive 5-piperazin-1-yl-1,3,4-thiadiazol-2-amines rendered as valid substrates for Groebke-Blackburn type multicomponent reaction with aldehydes and isocyanides using TMSCl as a promoter. Tetrah. Lett., 49(36), 5241–5243(2008).

  12. Balakin K. V.; Ivanenkov Y. A.; Tkachenko S. E.; Kiselyov A. S.; Ivachtchenko A. V. Regulators of chemokine receptor activity as promising anticancer therapeutics. Targets, 8(4), 299–340 (2008).
  13. Koryakova A. G.; Ivanenkov Y. A.; Ryzhova E. A.; Bulanova E. A.; Karapetian R. N.; Mikitas O. V.; Katrukha E. A.; Kazey V. I.; Kysil V. M.; Kravchenko D. V.; Lavrovsky Y. V.; Korzinov O. M.; Ivachtchenko A. V. Novel aryl and heteroaryl substituted N-[3-(4-phenylpiperazin-1-yl)propyl]-1,2,4-oxadiazole-5-carboxamides as selective GSK-3 inhibitors. Bioorg. Med. Chem. Lett., 18(12), 3661–3666 (2008).

  14. Ivachtchenko A. V.; Tkachenko S. E.; Okun I. M.; Savchuk N. F.; Miroshnichenko I. I.; Lelishentsev A. A.; Kalmykov Yu. M.; Fedotov Yu. A.; Ivachtchenko A. A. Determining amlodipine in blood plasma by liquid chromatography coupled to tandem mass spectrometry. Pharm. Chem. J., 42(8), 493–495 (2008).

  15. Salimov R., Tkachenko S. P1-019: Effect of Tacrine and Dimebon on scopolamine- and dizocipline-induced memory impairment in mice. Alzheimer’s and Dementia. 2008; 4(4); Supplement 1: T211.

  16. Tkachenko S.E. P2-478: Discovery and in vivo evaluation of potent 5-HT6 receptor antagonists for cognition enhancement in treating Alzheimer’s disease. Alzheimer’s and Dementia. 2008; 4(4); Supplement 1: T514.

  17. Sandulenko Yu.B., Ivashchenko A.V., Kravchenko D.V., Tkachenko S.E., Vvedensky V.Yu. Parallel solid-phase synthesis of novel 3,7-diazabicyclo[3.3.1]nonane derivatives starting from natural alkaloid cytisine. Russian Chemical Bulletin. 2008; 57(9): 1999-2004.

  18. Ivanenkov Y.A., Balakin K.V., Tkachenko S.E. New approaches to the treatment of inflammatory disease: focus on small-molecule inhibitors of signal transduction pathways. Drugs in R&D. 2008; 9(6): 397-434.

  19. Balakin K.V., Ivanenkov Y.A., Tkachenko S.E., Kiselyov A.S., Ivachtchenko A.V. Regulators of chemokine receptor activity as promising anticancer therapeutics. Current Cancer Drug Targets. 2008; 8(4): 299-34.

  20. Okun I., Balakin K.V., Tkachenko S.E., Ivachtchenko A.V. Caspase activity modulators as anticancer agents. Anti-Cancer Agents in Medicinal Chemistry. 2008; 8(3): 322-341.

  21. Lavrovsky Y, Ivanenkov YA, Balakin KV, Medvedeva DA, Ivachtchenko AV. CXCR4 receptor as a promising target for oncolytic drugs. Mini Reviews in Medicinal Chemistry. 2008; 8(11): 1075-87.

  22. Chekmarev DS, Kholodovych V, Balakin KV, Ivanenkov Y, Ekins S, Welsh WJ. Shape signatures: new descriptors for predicting cardiotoxicity in silico. Chemical Research in Toxicology. 2008; 21(6): 1304-14.

  23. Koryakova AG, Ivanenkov YA, Ryzhova EA, Bulanova EA, Karapetian RN, Mikitas OV, Katrukha EA, Kazey VI, Okun I, Kravchenko DV, Lavrovsky YV, Korzinov OM, Ivachtchenko AV. Novel aryl and heteroaryl substituted N-[3-(4-phenylpiperazin-1-yl)propyl]-1,2,4-oxadiazole-5-carboxamides as selective GSK-3 inhibitors. Bioorganic & Medicinal Chemistry Letters. 2008; 18(12): 3661-6.

  24. Balakin K.V., Ivanenkov Y.A., Ivachtchenko A.A. Computer methods for predicting the target-specific activity in the development of new anticancer compounds. Proceedings of the III Congress of Pharmacology Russia, Saint-Petersburg, 23–27 September, 2008, Abstr 45.

  25. Balakin K.V., Ivanenkov Y.A., et al. Create application systems generate knowledge about the pharmacological properties of chemical compounds based on databases of chemical and biological data and mathematical algorithms of multiparametric analysis objects. The structure of the Program of the Presidium of RAS “Basic Sciences – Medicine” in 2008. Abstracts “Conferences and seminars on the scientific directions of the Program in 2008″. Moscow, “Word”, 2008, pp. 98-99.