Publications in 2009

  1. Alyabyev S.B., Kravchenko D.V., Ivachtchenko A.V. Functionalization of oxadiazolyl indole systems. J. Org. Chem., 2009, 45 (5), 719-724.

  2. Sapegin A.V., Sakharov V.N., Smirnov A. V., Ivachtchenko A. V., Dorogov M.V. Development of the method of synthesis benzoxyazepinones by denitro cyclization reactions. Proceedings of the Universities, Chemistry and Chemical Engineering. Technology, 2009, 52 (4), 214-218.

  3. Sapegin A.V., Khristolyubova T.A., Kalandadze L.S, Smirnov A. V., Ivachtchenko A. V., Dorogov M.V. The synthesis and prediction of properties of new pharmacologically important polyheterocyclic systems containing fragments pyridyl benzoxyazepinone and oxadiazole. Proceedings of the Universities, Chemistry and Chemical Engineering. Technology, 2009, 52 (7), 14-20.

  4. Vihrov I. A., Smirnov A. B., Ivachtchenko A. B., Sapegin A. B., Khristolyubova T.A., Shalygina E.E. Using denitro cyclization reaction in the synthesis of benzanelirovannyh lactam systems. Proceedings of the Universities, Chemistry and Chemical Engineering. Technology, 2009, 52(10), 29–31.

  5. Ivachtchenko A.V., Mitkin O.D., Kadieva M.G., Dubrovskaya E. C., Okun I.M., Tkachenko S.E. Substituted 2,3,4,5-tetrahydro-1H-pyrido [4,3-b] indoles – Histamine H1 receptor antagonists. Proceedings of the Universities, Chemistry and Chemical Engineering. Technology, 2009, 52(10), 31–37.

  6. Ivachtchenko A.V., Mitkin O.D., Kuznetsova I. V., Kadieva M.G., Ivchenko A. N. Synthesis of 2,3,4,5-tetrahydro-1H-γ-carboline carboxylic acids and their derivatives. Proceedings of the Universities, Chemistry and Chemical Engineering. Technology, 2009, 52(10), 38–45.

  7. Potapov V. V., Ilyin A. P., Kravchenko D. B., Fetisova N. A., Ivachtchenko A.V. Synthesis of substituted 3-methyl-1-oxo-2,3,4,5-tetrahydro-1H-benzo [c] azepin-3-carboxamides. Proceedings of the Universities, Chemistry and Chemical Engineering. Technology, 2009, 52(10), 46–51.

  8. Ivachtchenko A.V., Ilyin A. P., Kravchenko D. B., Potapov V. V. One-step synthesis of 5-oxo-1,3,4,5-tetrahydropyrrolo [4,3,2-de] isoquinoline-3-carboxamides. Proceedings of the Universities, Chemistry and Chemical Engineering. Technology, 2009, 52(10), 51–55.

  9. Ivachtchenko A.V., Frolov E.B., Mitkin O.D., Tkachenko S.E., Khvat A.V. Synthesis of 5- and 8-substituted 2-methyl-2,3,4,5-tetrahydro-1H-γ-carbolines – anatogonists of serotonin 5-HT6 receptor. Proceedings of the Universities, Chemistry and Chemical Engineering. Technology, 2009, 52(10), 55–60.

  10. Ivachtchenko A.V., Frolov E.B., Mitkin O.D., Dubrovskaya E. C., Okun I.M., Golovina E. S., Tkachenko S.E., Khvat A.V. Synthesis substituted 1,2,3,4,5,6-hexahydro azepino [4,3, -b] indoles. Proceedings of the Universities, Chemistry and Chemical Engineering. Technology, 2009, 52(10), 66–72.

  11. Ivachtchenko A.V., Frolov E.B., Mitkin O.D., Golovina E. S., Dubrovskaya E. C., Tkachenko S.E., Khvat A.V. Synthesis of 6-substituted and benzyl-6- (pyridinyl methyl) -1,2,3,4,5,6-hexahydroazepine [4,3-b] indoles. Proceedings of the Universities, Chemistry and Chemical Engineering. Technology, 2009, 52(10), 73–77.

  12. Ivachtchenko A.V., Mitkin O.D., Kysil V.M., Frolov E.B., Tkachenko S.E. The synthesis of substituted 5-sulfonyl-2,3,4,5-tetrahydro-1H-γ-carboline. Proceedings of the Universities, Chemistry and Chemical Engineering. Technology, 2009, 52(10), 78–83.

  13. Ivachtchenko A.V., Mitkin O.D., Kysil V.M., Frolov E.B., Tkachenko S.E. Synthesis of substituted 2-sulfonyl-2,3,4,5-tetrahydro-1H-γ-carboline. Proceedings of the Universities, Chemistry and Chemical Engineering. Technology, 2009, 52(10), 83–87.

  14. Ivachtchenko A.V., Mitkin O.D., Frolov E.B., Golovina E. S., Okun I. M., Tkachenko S.E., Khvat A.V. Synthesis of 6-substituted 1,2,3,4,5,6-hexahydroazepino [4,3-b] indoles. Proceedings of the Universities, Chemistry and Chemical Engineering. Technology, 2009, 52(10), 88–93.

  15. Potapov V. V., Fetisova N. A., Nikitin A. V., Ivachtchenko A. V. One-step assembly of novel carbamoyl substituted 6-oxo-4,5,6,11-tetrahydropyrrolo[1,2-b][2,5]benzodiazo-cine. Tetrah. Lett., 2009, 50(23), 2790–2792.

  16. Kysil V., Khvat A., Tsirulnikov S., Tkachenko S., Ivachtchenko A. Multicomponent approach to unique 1,4-diazepine-2-amines. Tetrah. Lett., 2009, 50(24), 2854–2856.

  17. Tsirulnikov S., Nikulnikov M., Kysil V., Ivachtchenko A., Krasavin M. Streamlined access to 2,3-dihydropyrazino[1,2-a]indole-1,4-diones via Ugi reaction followed by microwave-assisted cyclization. Tetrah. Lett., 2009, 50(39), 5529–5531.

  18. Ivachtchenko A. V.; Frolov E. B.; Mitkin O. D.; Kysil V. M.; Khvat A. V.; Tkachenko S. E. Synthesis and Biological Evaluation of Novel 5,8-Disubstituted-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoles as 5-HT6 and H1 Receptors Antagonists. Arch. Pharm., 2009, 342(12), 740–747.

  19. Alyab’ev S. B.; Kravchenko D. V.; Ivachtchenko A. V. Synthesis and functionalization of the 3-(1,3,4-oxadiazol-2-yl)-1h-indoles. Chem. Heterocycl. Comp., 2009, 45(10), 1270–1275.

  20. Potapov V. V.; Fetisova N. A.; Nikitin A. V.; Ivachtchenko A. V. A convenient synthesis of heterocyclic compounds containing 11-oxo-6,11,12,13-tetrahydrodiben-zo[b,g][1,5]oxazonine fragment. Mend. Commun., 2009, 19(5), 287–289.

  21. Lakner F. J.; Parker M. A.; Rogovoy,B.; Khvat A.; Ivachtchenko A. Synthesis of novel trisubstituted imidazolines. Synthesis, 2009, 1987–1990.

  22. Ivachtchenko A. V.; Frolov E. B.; Mitkin O. D.; Kysil V. M.; Khvat A. V.; Okun I. M.; Tkachenko S. E. Synthesis and biological evaluation of novel γ-carboline analogues of Dimebon as potent 5-HT6 receptor antagonists. Bioorg. Med. Chem. Lett., 2009, 19(12), 3183–3187.

  23. Nikulnikov M.; Tsirulnikov S.; Kysil V.; Ivachtchenko A.; Krasavin,M. Tert-Butyl isocyanide as a convertible reagent in Ugi reaction: microwave-assisted preparation of 5,6-dihydropyrazolo[1,5-a]pyrazine-4,7-diones. Synlett, 2009, 260–262.

  24. Ivachtchenko A. V.; Kysil V. M.; Tkachenko S. E.; Kiselyov A. S.; Ivanenkov Y. A.; Balakin K. V. Nonpeptide small molecule inhibitors of caspases (Review). In: Design of Caspase Inhibitors as Potential Clinical Agents, 2009, 93–122. Publisher: CRC Press, Boca Raton, Florida.

  25. Ryzhova E. A.; Koryakova A. G.; Bulanova E. A.; Mikitas O. V.; Karapetyan R. N.; Lavrovsky, Y. V.; Ivachtchenko A. V. Synthesis, molecular docking, and biological testing of new selective inhibitors of glycogen synthase kinase 3β. Pharm. Chem. J., 2009, 43(3), 148–153.

  26. Balakin K.V., Ivanenkov Y.A., Bovina. E.V. Methods of non-linear mapping to predict the pharmacological properties of chemical compounds (plenary report). VII th Conference Youth Scientific School, UFA, 1-5 July 2009.

  27. Okun I., Tkachenko S.E., Khvat A., Mitkin O., Kazey V., Ivachtchenko V.A. From Anti-allergic to Anti-Alzheimer’s: Molecular Pharmacology of Dimebon. Current Alzheimer Research. 2009 Nov 26. [Epub ahead of print].

  28. Ivachtchenko A.V., Frolov E.B., Mitkin O.D., Kysil V.M., Khvat A.V., Tkachenko S.E. Synthesis and Biological Evaluation of Novel 5,8-Disubstituted-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b] indoles as 5-HT(6) and H(1) Receptors Antagonists. Archiv der Pharmazie (Weinheim). 2009; 342(12):740-747.

  29. Tkachenko S., Ivachtchenko A., Okun I., Lavrovsky Y., Mitkin O., Salimov R. P4-212: Comparision of highly selective and non-selective 5-HT6 receptor antagonists in in vitro and in vivo neurodegenerative models. Alzheimer’s and Dementia. 2009; 4(4); Supplement 1: P492.

  30. Ivachtchenko A.V., Frolov E.B., Mitkin O.D., Kysil V.M., Khvat A.V., Okun I.M., Tkachenko S.E. Synthesis and biological evaluation of novel γ-carboline analogues of Dimebon as potent 5-HT6 receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 2009; 19(12): 3183-3187.

  31. Kysil V.M., Khvat A., Tsirulnikov S., Tkachenko S., Ivachtchenko A. Multicomponent approach to unique 1,4-diazepine-2-amines. Tetrahedron Letters. 2009; 50(24): 2854-2856.

  32. Balakin KV, Ivanenkov YA, Savchuk NP. Compound library design for target families. Methods Molecular Biology. 2009; 575: 21-46.

  33. Ivanenkov YA, Savchuk NP, Ekins S, Balakin KV. Computational mapping tools for drug discovery. Drug Discovery Today. 2009; 14(15-16): 767-75.

  34. Bushkova E, Parchinsky V, Krasavin M. Efficient entry into hydrazinopeptide-like structures via sequential Ugi reactions. Molecular Diversity. 2009 Nov 10. [Epub ahead of print]

  35. Krasavin M, Karapetian R, Konstantinov I, Gezentsvey Y, Bukhryakov K, Godovykh E, Soldatkina O, Lavrovsky Y, Sosnov AV, Gakh AA. Discovery and potency optimization of 2-amino-5-arylmethyl-1,3-thiazole derivatives as potential therapeutic agents for prostate cancer. Archiv der Pharmazie (Weinheim). 2009; 342(7): 420-7.

  36. Krasavin M, Shkavrov S, Parchinsky V, Bukhryakov K. Imidazo[1,2-a]quinoxalines accessed via two sequential isocyanide-based multicomponent reactions. Journal of Organic Chemistry. 2009; 74(6): 2627-9.