Publications in 2010

  1. Ivachtchenko A.V., Mitkin O.D., Kadieva М.G., Tkachenko S.E. The synthesus and physiological activity of 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoles (Review). Russian Chem. Rev., 2010, 79(4), 325-347.

  2. Ivachtchenko A.V., Mitkin O.D., Kadieva М.G., Tkachenko S.E. The synthesus and physiological activity of 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoles (Review). Russian Chem. Rev., 2010, 79(4), 285-306.

  3. Ivachtchenko A. V., Ivanenkov, Y.A., Kysil V.M., Krasavin, M.Y., Ilyin A.P. Multicomponent Reactions of Isocyanides in the Synthesis of Heterocycles (Review). Russian Chem. Rev., 2010, 79, 787–817.

  4. Ivachtchenko A. V., Ivanenkov, Y.A., Kysil V.M., Krasavin, M.Y., Ilyin A.P. Multicomponent Reactions of Isocyanides in the Synthesis of Heterocycles (Review). Russian Chem. Rev., 2010, 79 (9), 861-893.

  5. Ivachtchenko A.V., Frolov E.B., Mitkin O.D., Tkachenko S.E., Okun I.M., Khvat A.V. Synthesis and biological activity of 5-styryl and 5-phenethyl-substituted 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoles. Bioorg. Med. Chem. Lett., 2010, 20(1), 78–82.

  6. Ivachtchenko A.V., Dmitriev D.E., Golovina E.S., Dubrovskaya E.S., Kadieva M.G., Koryakova A.G., Kysil V.M., Mitkin O.D., Tkachenko S.E., Okun I.M., Vorobiov A.A. Synthesis of cycloalkane-annelated 3-phenylsulfonyl-pyrazolo[1,5-a]pyrimidines and their evaluation as 5-HT6 receptor antagonists. Bioorg. Med. Chem. Lett., 2010, 20(7), 2133–2136.

  7. Tsirulnikov S., Kysil V., Ivachtchenko A., Krasavin M. Trimethylsilyl Chloride as a Promoter for the Groebke-Blackburn Reaction: Preparation of Imidazo[2,1-b][1,3]Benzothiazoles. Synth. Comm., 2010, 40(1), 111–119.

  8. Ivachtchenko A.V., Mitkin O.D., Tkachenko S.E., Okun I.M., Kysil V.M. 8-Sulfonyl-substituted tetrahydro-1H-pyrido[4,3-b]indoles as 5-HT6 receptor antagonists. Eur. J. Med. Chem., 2010, 45(2), 782–789.

  9. Ivachtchenko A.V., Golovina E.S., Kadieva M.G., Koryakova A.G., Kovalenko S.M., Mitkin O.D., Okun I.M. Ravnyeyko I.M., Tkachenko S.E., Zaremba O.V. Synthesis and biological study of 3-(phenylsulfonyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidines as potent and selective serotonin 5-HT6 receptor antagonists. Bioorg. Med. Chem., 2010, 18, 5282–5290.

  10. Okun I.M., Tkachenko S.E., Khvat A.V., Mitkin O.D., Kazey V.I., Ivachtchenko A.V. From anti-allergic to anti-Alzheimer’s: Molecular pharmacology of Dimebon. Curr. Alzheimer Res., 2010, 7(2), 97–112.

  11. Ivachtchenko A.V., Golovina E.S., Kadieva M.G., Koryakova A.G., Kysil V.M., Mitkin O.D., Okun I.M., Ravnyeyko I.M., Tkachenko S.E., Zaremba O. Solution Phase Parallel Synthesis of Substituted 3-Phenylsulfonyl-[1,2,3]triazolo[1,5-a]quinazolines: Selective Serotonin 5-HT(6) Receptor Antagonists. J. Comb. Chem., 2010, 12, 445–452.

  12. Ivachtchenko A.V., Dmitriev D.E., Golovina E.S., Kadieva M.G., Koryakova A.G., Kysil V.M., Mitkin O.D., Okun I.M., Tkachenko S.E., Vorobiov A.A. (3-Phenylsulfonylcycloalkano[e and d]pyrazolo[1,5-a]pyrimidin-2-yl)amines: Potent and Selective Antagonists of the Serotonin 5-HT(6) Receptor. J. Med. Chem., 2010, 53, 5186–5196.

  13. Ivachtchenko A.V., Ivanenkov Y.A., Tkachenko S.E. 5-hydroxytryptamine subtype 6 receptor modulators: a patent survey. Expert Opin. Ther. Pat., 2010, 20(7), 1171-1196.
  14. Ivachtchenko A.V., Frolov E.B., Mitkin O.D., Tkachenko S.E., Khvat A.V. Synthesis of hydrogenated 2,7-dimethylpyrrolo[3,4-b]indoles – analogs of Dimebon. Heterocyclic Comp., 2010, 46(2), 170-178.

  15. Ivachtchenko A.V., Frolov E.B., Mitkin O.D., Tkachenko S.E., Khvat A.V. Synthesis of hydrogenated 2,7-dimethylpyrrolo[3,4-b]indoles – analogs of Dimebon. Heterocyclic Comp., 2010, 209-220.

  16. Ivachtchenko A.V., Kadieva M.G., Kravchenko D.V., Lavrovsky Y.V., Mitkin O.D., Salimov R.M., Fedotov Y. A. Antiallergic properties ethyl 3- (8-fluoro-2-methyl-2,3,4,5-tetrahydro-pyrido [4,3-b] indol-5-yl) propionate dihydrochloride. Exper. Clinical. Farmacol., 2010, 73 (3), 28-30.

  17. Ivachtchenko A.V., Kadieva M.G., Mitkin O.D., Kravchenko D.V., Salimov R.M., Skrabelinskaya E.I.,Fedotov Y. A., Lavrovsky Y.V. Study of the toxicity of ethyl 3- (8-fluoro-2-methyl-2,3,4,5-tetrahydropyrido [4,3-b indol-5-yl) propionate dihydrochloride having antiallergic properties. Exper. Clinical. Farmacol., 2010, 73 (6), 33-35.

  18. Ivachtchenko A.V., Mitkin O.D., Okun I.M., Salimov R.M., Fedotov Y. A. Substituted 2,3,4,5-tetrahydro-1H-γ-carbolines – new antagonists of H1 histamine receptors. Exper. Clinical. Farmacol., 2010, 73 (11), 25-29.

  19. Ivaschenko A.V., Frolov E.B., Mitkin O.D., Tkachenko S.E., Khvat A.V. Synthesis and Biological Evaluation of Novel Bioisosteric Analogues of DimebonTM. LDDD, 2010, 7(6), 446-451.

  20. Ivachtchenko A.V., Yamanushkin P.M., Mitkin O.D., Kiselev O.I. Bromination of indomethacin. Mendeleev Comm., 2010, 20, 111-112.

  21. T.G. Volkova, Y.A. Ivanenkov, et al. Prediction of biological activity of benzylideneaniline: the impact of the structure and conformation. XV Symposium on intermolecular interactions and conformations of molecules June 14-18, 2010, Petrozavodsk.

  22. Ivachtchenko A.V., Dmitriev D.E., Golovina E.S., Dubrovskaya E.S., Kadieva M.G., Koryakova A.G., Kysil V.M., Mitkin O.D., Tkachenko S.E., Okun I.M., Vorobiov A.A. Synthesis of cycloalkane-annelated 3-phenylsulfonyl-pyrazolo[1,5-a]pyrimidines and their evaluation as 5-HT(6) receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 2010 Feb 14. in press.

  23. Kysil V., Khvat A., Tsirulnikov S., Tkachenko S, Williams C., Churakova M., Ivachtchenko A. General Multicomponent Strategy for the Synthesis of 2-Amino-1,4-diazaheterocycles: Scope, Limitations, and Utility. European Journal of Organic Chemistry. 2010; 1525-1543.

  24. Ivachtchenko A., Golovina E., Kadieva M., Koryakova A., Kovalenko S., Mitkin O., Okun I., Ravnyeyko I., Tkachenko S., Zaremba O. Solution Phase Parallel Synthesis of Substituted 3-Phenylsulfonyl-[1,2,3]triazolo[1,5-a]quinazolines – Selective Serotonin 5-HT(6) Receptor Antagonists. Journal of Combinatorial Chemistry. 2010; in press.

  25. Ivachtchenko A.V., Mitkin O.D., Tkachenko S.E., Okun I.M., Kysil V.M. 8-Sulfonyl-substituted tetrahydro-1H-pyrido[4,3-b]indoles as 5-HT(6) receptor antagonists. European Journal of Medicinal Chemistry. 2010; 45(2): 782-789.

  26. Ivachtchenko A.V., Frolov E.B., Mitkin O.D., Tkachenko S.E., Okun I.M., Khvat A.V. Synthesis and biological activity of 5-styryl and 5-phenethyl-substituted 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoles. Bioorganic & Medicinal Chemistry Letters. 2010; 20(1): 78-82.