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Androgen Receptor Antagonists Library

4,300 Compounds

The library has been designed around 21 core structures (in fact, this is not limit and more cores can be identified for further library expansion).

Each of these cores is able to provide 1-3 scaffolds, so entire library has been populated around 51 scaffolds.
Total number of populated library members – 14,278

23 scaffolds have been finally selected and prioritized for the library synthesis:
Priority # 1 – 14 scaffolds,
Priority # 2 – 4 scaffolds,
Priority # 3 – 5 scaffolds;
4.3K-members Library around 17 scaffolds has been synthesized.

Medicinal and Computational Chemistry Dept., ChemDiv, Inc.
12760 High Bluff Dr, San Diego, CA, 92130
Phone: + 1 916 234 0888
Fax: +1 858 794 4931
Email: ChemDiv@chemdiv.com

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