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Category: Blog

In the last few years, the evolution of science has moved at an exponential rate. Presently, medical …

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Historically, natural products have been pharma’s treasure trove. According to the Natural Products Library Initiative at the Scripps Research Institute, “from 1940s to date, 131 (74.8%) out of 175 small molecule …

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Walker et al. (1999) Nature 402, 313-320

Compared to some of the other big targets in drug discovery, PI3 kinase (PI3K) inhibition is clinically advanced. …

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In the world of cancer drug discovery, the Ras family of G proteins – K-Ras, H-Ras and N-Ras – is a so-far unclaimed prize. Given that a third of all tumors have mutations in a RAS protein, with …

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