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Proteases annotated library 320

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Desirable size of the custom library selection:
Amount:
Mg
  • Mg
  • uMol
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•Proteases are enzymatic proteins that cleave specific peptide bonds withing other functional proteins

•Physiologically the protease enzymatic activity can be modulated by
-Mimetics of peptide motifs that bind at a catalytic site
-Chelators of specific metal ions that often used by proteases as cofactors

•Proteases are well recognized as important therapeutic targets for

-Infections, e.g. antibacterial, antiviral, antimalarials
-Inflammatory diseases, e.g. fibrosis, NSAID painkillers, joint stiffness
-Cardiovascular system, e.g. blood pressure regulation, thrombosis
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