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CNS Targets

44,000 Compounds

• Library of compounds acting on central nervous system (CNS) targets
• In CNS drug discovery the drug targets are used for targeting CNS and neurological related diseases
like Parkinson’s disease, Alzheimer’s disease, schizophrenia, drug dependence, etc.
• Activity of drug target as a nucleic acid or a protein (e.g. an enzyme, a receptor) can be modulated by
a small-molecular-weight chemical compound.
• As the discovery, identification, characterization and validation of novel human drug targets for CNS
disease biology, and the emergence of new mechanisms and targets for misfolded proteins, tau,
GCPRs, kinase inhibitors, neuroinflammation, etc. continues to grow; this library is a valuable tool for the neurological and CNS drug discovery.

A unique collection of small molecule compounds selected for CNS protein targets
❑ Therapeutically relevant CNS targets (98 protein sub-families/units targets in total)
❑ Recent literature data from 846 research papers and patents published since 2014
❑ The recent X-Ray and Cryo-EM structures from PDB
❑ Comprehensive CNS Targets Platform Library : 44,000 compounds

Examples of Structures

Medicinal and Computational Chemistry Dept., ChemDiv, Inc.
12760 High Bluff Dr, San Diego, CA, 92130
Phone: + 1 916 234 0888
Fax: +1 858 794 4931
Email: ChemDiv@chemdiv.com

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