As the name implies, peptidomimetics are organic molecules that mimic the action of peptides. These molecules may structurally resemble peptides but are distinctly different in terms of their side chains or their molecular backbones. Since the mode of action for a small-molecule and a peptidomimetic is similar, confusion sometimes arises with regard to the classification of the molecule as being a peptidomimetic or simply a small organic molecular mimic. Nevertheless, interactions with proteins can be mediated by other molecules with intermediate molecular masses instead of the low molecular weights associated with small-molecules or peptidomimetics.
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