7180-0018 Screening compound: 4-(3-chlorophenyl)-3-(2-methoxyphenyl)-2-phenyl-1,2,4-oxadiazolidin-5-one

7180-0018 Screening compound: 4-(3-chlorophenyl)-3-(2-methoxyphenyl)-2-phenyl-1,2,4-oxadiazolidin-5-one
7180-0018 Screening compound: 4-(3-chlorophenyl)-3-(2-methoxyphenyl)-2-phenyl-1,2,4-oxadiazolidin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 7180-0018
4-(3-chlorophenyl)-3-(2-methoxyphenyl)-2-phenyl-1,2,4-oxadiazolidin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

7180-0018

Molecular Formula

C21H17ClN2O3 (C21 H17 ClN2 O3)

Compound Name

4-(3-chlorophenyl)-3-(2-methoxyphenyl)-2-phenyl-1,2,4-oxadiazolidin-5-one

IUPAC name

4-(3-chlorophenyl)-3-(2-methoxyphenyl)-2-phenyl-124-oxadiazolidin-5-one

SMILES

COc1c(C(N2c3cccc(Cl)c3)N(c3ccccc3)OC2=O)cccc1

InChI

InChI=1S/C21H17ClN2O3/c1-26-19-13-6-5-12-18(19)20-23(17-11-7-8-15(22)14-17)21(25)27-24(20)16-9-3-2-4-10-16/h2-14,20H,1H3/t20-/m0/s1

InChI Key

SKIZHDCFWFCMBW-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD14712300

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.83

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.043

Distribution Coefficient, logD

5.043

Water Solubility, LogSw

-5.16

Polar Surface Area

37.153

Acid Dissociation Constant (pKa)

20.51

Base Dissociation Constant (pKb)

0.92

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

9.50

7180-0018 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Neuropeptide S Library (2850 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Nervous system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with 7180-0018 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 7180-0018?
Check Price and Availability of 7180-0018, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 7180-0018 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 7180-0018
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 7180-0018
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 7180-0018 available by request