F368-1416 Screening compound: 1-{[1,4'-bipiperidin]-1'-yl}-3-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]propan-1-one

F368-1416 Screening compound: 1-{[1,4'-bipiperidin]-1'-yl}-3-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]propan-1-one
F368-1416 Screening compound: 1-{[1,4'-bipiperidin]-1'-yl}-3-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F368-1416
1-{[1,4'-bipiperidin]-1'-yl}-3-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F368-1416

Molecular Formula

C23H31FN4O (C23 H31 FN4 O)

Compound Name

1-{[1,4'-bipiperidin]-1'-yl}-3-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]propan-1-one

IUPAC name

1-{[14'-bipiperidin]-1'-yl}-3-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]propan-1-one

SMILES

Cn(cc1CCC(N(CC2)CCC2N2CCCCC2)=O)nc1-c(cc1)ccc1F

InChI

InChI=1S/C23H31FN4O/c1-26-17-19(23(25-26)18-5-8-20(24)9-6-18)7-10-22(29)28-15-11-21(12-16-28)27-13-3-2-4-14-27/h5-6,8-9,17,21H,2-4,7,10-16H2,1H3

InChI Key

PAFXATLYFUAJTG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27120058

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.52

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.801

Distribution Coefficient, logD

-0.755

Water Solubility, LogSw

-2.84

Polar Surface Area

34.537

Acid Dissociation Constant (pKa)

21.56

Base Dissociation Constant (pKb)

10.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

56.50

F368-1416 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F368-1416 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F368-1416?
Check Price and Availability of F368-1416, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F368-1416 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F368-1416
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F368-1416
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F368-1416 available by request