F449-1427 Screening compound: 2-{[5-(tert-butylamino)-6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl](methyl)amino}-N-[(furan-2-yl)methyl]-N-methylacetamide

F449-1427 Screening compound: 2-{[5-(tert-butylamino)-6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl](methyl)amino}-N-[(furan-2-yl)methyl]-N-methylacetamide
F449-1427 Screening compound: 2-{[5-(tert-butylamino)-6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl](methyl)amino}-N-[(furan-2-yl)methyl]-N-methylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F449-1427
2-{[5-(tert-butylamino)-6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl](methyl)amino}-N-[(furan-2-yl)methyl]-N-methylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F449-1427

Molecular Formula

C24H30N6O3S (C24 H30 N6 O3 S)

Compound Name

2-{[5-(tert-butylamino)-6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl](methyl)amino}-N-[(furan-2-yl)methyl]-N-methylacetamide

IUPAC name

2-{[5-(tert-butylamino)-6-(4-methoxyphenyl)imidazo[21-b][134]thiadiazol-2-yl](methyl)amino}-N-[(furan-2-yl)methyl]-N-methylacetamide

SMILES

CC(C)(C)Nc1c(-c(cc2)ccc2OC)nc2sc(N(C)CC(N(C)Cc3ccco3)=O)nn12

InChI

InChI=1S/C24H30N6O3S/c1-24(2,3)26-21-20(16-9-11-17(32-6)12-10-16)25-22-30(21)27-23(34-22)29(5)15-19(31)28(4)14-18-8-7-13-33-18/h7-13,26H,14-15H2,1-6H3

InChI Key

OQHBRSQXCCHPKO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27642369

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

482.61

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.148

Distribution Coefficient, logD

4.148

Water Solubility, LogSw

-4.19

Polar Surface Area

64.469

Acid Dissociation Constant (pKa)

16.34

Base Dissociation Constant (pKb)

3.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

F449-1427 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with F449-1427 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F449-1427?
Check Price and Availability of F449-1427, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F449-1427 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F449-1427
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F449-1427
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F449-1427 available by request