0422-0034 Screening compound: 2-[(E)-(hydroxyimino)methyl]quinolin-8-ol

0422-0034 Screening compound: 2-[(E)-(hydroxyimino)methyl]quinolin-8-ol
0422-0034 Screening compound: 2-[(E)-(hydroxyimino)methyl]quinolin-8-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound 0422-0034
2-[(E)-(hydroxyimino)methyl]quinolin-8-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

0422-0034

Molecular Formula

C10H8N2O2 (C10 H8 N2 O2)

Compound Name

2-[(E)-(hydroxyimino)methyl]quinolin-8-ol

IUPAC name

2-[(E)-(hydroxyimino)methyl]quinolin-8-ol

SMILES

Oc1c2nc(/C=N/O)ccc2ccc1

InChI

InChI=1S/C10H8N2O2/c13-9-3-1-2-7-4-5-8(6-11-14)12-10(7)9/h1-6,13-14H

InChI Key

QTVCYMRHAGWXMB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00168964

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

188.19

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

1.893

Distribution Coefficient, logD

1.885

Water Solubility, LogSw

-2.34

Polar Surface Area

55.398

Acid Dissociation Constant (pKa)

9.21

Base Dissociation Constant (pKb)

4.67

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

0422-0034 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Proteases
  • Phosphatases

References: we are preparing a list of scientific research reports with 0422-0034 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 0422-0034?
Check Price and Availability of 0422-0034, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 0422-0034 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 0422-0034
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 0422-0034
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 0422-0034 available by request