0633-0066 Screening compound: 1-{1-[(2,4-dichlorophenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidin-4-yl}-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine

0633-0066 Screening compound: 1-{1-[(2,4-dichlorophenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidin-4-yl}-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine
0633-0066 Screening compound: 1-{1-[(2,4-dichlorophenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidin-4-yl}-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound 0633-0066
1-{1-[(2,4-dichlorophenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidin-4-yl}-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

0633-0066

Molecular Formula

C25H24Cl2N6 (C25 H24 Cl2 N6)

Compound Name

1-{1-[(2,4-dichlorophenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidin-4-yl}-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine

IUPAC name

1-{1-[(24-dichlorophenyl)methyl]-1H-pyrazolo[34-d]pyrimidin-4-yl}-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine

SMILES

Clc1cc(Cl)c(Cn2ncc3c(N4CCN(C/C=C/c5ccccc5)CC4)ncnc23)cc1

InChI

InChI=1S/C25H24Cl2N6/c26-21-9-8-20(23(27)15-21)17-33-25-22(16-30-33)24(28-18-29-25)32-13-11-31(12-14-32)10-4-7-19-5-2-1-3-6-19/h1-9,15-16,18H,10-14,17H2

InChI Key

LPOJYIYWLCOAPO-UHFFFAOYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

479.41

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.925

Distribution Coefficient, logD

5.915

Water Solubility, LogSw

-6.41

Polar Surface Area

41.243

Acid Dissociation Constant (pKa)

21.11

Base Dissociation Constant (pKb)

5.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

0633-0066 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 0633-0066 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 0633-0066?
Check Price and Availability of 0633-0066, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 0633-0066 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 0633-0066
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 0633-0066
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 0633-0066 available by request