0833-0149 Screening compound: 5-{[1,1'-biphenyl]-4-yl}-1,3-diphenyl-4,5-dihydro-1H-pyrazole

0833-0149 Screening compound: 5-{[1,1'-biphenyl]-4-yl}-1,3-diphenyl-4,5-dihydro-1H-pyrazole
0833-0149 Screening compound: 5-{[1,1'-biphenyl]-4-yl}-1,3-diphenyl-4,5-dihydro-1H-pyrazole alternative view

Chemical Structure Depiction of ChemDiv screening compound 0833-0149
5-{[1,1'-biphenyl]-4-yl}-1,3-diphenyl-4,5-dihydro-1H-pyrazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

0833-0149

Molecular Formula

C27H22N2 (C27 H22 N2)

Compound Name

5-{[1,1'-biphenyl]-4-yl}-1,3-diphenyl-4,5-dihydro-1H-pyrazole

IUPAC name

5-{[11'-biphenyl]-4-yl}-13-diphenyl-45-dihydro-1H-pyrazole

SMILES

C(C1c(cc2)ccc2-c2ccccc2)C(c2ccccc2)=NN1c1ccccc1

InChI

InChI=1S/C27H22N2/c1-4-10-21(11-5-1)22-16-18-24(19-17-22)27-20-26(23-12-6-2-7-13-23)28-29(27)25-14-8-3-9-15-25/h1-19,27H,20H2/t27-/m1/s1

InChI Key

ICEQMQCLZOVEMI-HHHXNRCGSA-N

MDL Number (MFCD)

MFCD00489670

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.49

Hydrogen Bond Acceptors Count

1.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

2

Partition Coefficient, logP

7.177

Distribution Coefficient, logD

7.177

Water Solubility, LogSw

-6.64

Polar Surface Area

13.647

Acid Dissociation Constant (pKa)

17.56

Base Dissociation Constant (pKb)

-0.26

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

7.40

0833-0149 in Drug Discovery

Included in Screening Libraries

Proline Kinase Library (2105 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
  • Cancer
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with 0833-0149 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 0833-0149?
Check Price and Availability of 0833-0149, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 0833-0149 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 0833-0149
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 0833-0149
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 0833-0149 available by request