1186-0397 Screening compound: N-(5-benzoyl-4-phenyl-1,3-thiazol-2-yl)-4-cyanobenzamide

1186-0397 Screening compound: N-(5-benzoyl-4-phenyl-1,3-thiazol-2-yl)-4-cyanobenzamide
1186-0397 Screening compound: N-(5-benzoyl-4-phenyl-1,3-thiazol-2-yl)-4-cyanobenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 1186-0397
N-(5-benzoyl-4-phenyl-1,3-thiazol-2-yl)-4-cyanobenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1186-0397

Molecular Formula

C24H15N3O2S (C24 H15 N3 O2 S)

Compound Name

N-(5-benzoyl-4-phenyl-1,3-thiazol-2-yl)-4-cyanobenzamide

IUPAC name

N-(5-benzoyl-4-phenyl-13-thiazol-2-yl)-4-cyanobenzamide

SMILES

N#Cc(cc1)ccc1C(Nc1nc(-c2ccccc2)c(C(c2ccccc2)=O)s1)=O

InChI

InChI=1S/C24H15N3O2S/c25-15-16-11-13-19(14-12-16)23(29)27-24-26-20(17-7-3-1-4-8-17)22(30-24)21(28)18-9-5-2-6-10-18/h1-14H,(H,26,27,29)

InChI Key

VCZJHJJWSFFWJO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00994563

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

409.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.123

Distribution Coefficient, logD

5.086

Water Solubility, LogSw

-5.50

Polar Surface Area

64.398

Acid Dissociation Constant (pKa)

8.44

Base Dissociation Constant (pKb)

-5.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

1186-0397 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 1186-0397 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1186-0397?
Check Price and Availability of 1186-0397, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 1186-0397 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1186-0397
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1186-0397
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1186-0397 available by request