1195-0027 Screening compound: N'-(4-fluorobenzoyl)-2-hydroxy-N',2,2-triphenylacetohydrazide

1195-0027 Screening compound: N'-(4-fluorobenzoyl)-2-hydroxy-N',2,2-triphenylacetohydrazide
1195-0027 Screening compound: N'-(4-fluorobenzoyl)-2-hydroxy-N',2,2-triphenylacetohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 1195-0027
N'-(4-fluorobenzoyl)-2-hydroxy-N',2,2-triphenylacetohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1195-0027

Molecular Formula

C27H21FN2O3 (C27 H21 FN2 O3)

Compound Name

N'-(4-fluorobenzoyl)-2-hydroxy-N',2,2-triphenylacetohydrazide

IUPAC name

N'-(4-fluorobenzoyl)-2-hydroxy-N'22-triphenylacetohydrazide

SMILES

OC(C(NN(C(c(cc1)ccc1F)=O)c1ccccc1)=O)(c1ccccc1)c1ccccc1

InChI

InChI=1S/C27H21FN2O3/c28-23-18-16-20(17-19-23)25(31)30(24-14-8-3-9-15-24)29-26(32)27(33,21-10-4-1-5-11-21)22-12-6-2-7-13-22/h1-19,33H,(H,29,32)

InChI Key

RMKRZUILDZNEKF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00510478

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

440.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.045

Distribution Coefficient, logD

3.547

Water Solubility, LogSw

-4.28

Polar Surface Area

54.289

Acid Dissociation Constant (pKa)

7.07

Base Dissociation Constant (pKb)

-0.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

3.70

1195-0027 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with 1195-0027 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1195-0027?
Check Price and Availability of 1195-0027, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 1195-0027 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1195-0027
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1195-0027
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1195-0027 available by request