1269-5590 Screening compound: N'-[(E)-(4-hydroxy-3,5-dimethoxyphenyl)methylidene]pyridine-2-carbohydrazide

1269-5590 Screening compound: N'-[(E)-(4-hydroxy-3,5-dimethoxyphenyl)methylidene]pyridine-2-carbohydrazide
1269-5590 Screening compound: N'-[(E)-(4-hydroxy-3,5-dimethoxyphenyl)methylidene]pyridine-2-carbohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 1269-5590
N'-[(E)-(4-hydroxy-3,5-dimethoxyphenyl)methylidene]pyridine-2-carbohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1269-5590

Molecular Formula

C15H15N3O4 (C15 H15 N3 O4)

Compound Name

N'-[(E)-(4-hydroxy-3,5-dimethoxyphenyl)methylidene]pyridine-2-carbohydrazide

IUPAC name

N'-[(E)-(4-hydroxy-35-dimethoxyphenyl)methylidene]pyridine-2-carbohydrazide

SMILES

COc1cc(/C=N/NC(c2ncccc2)=O)cc(OC)c1O

InChI

InChI=1S/C15H15N3O4/c1-21-12-7-10(8-13(22-2)14(12)19)9-17-18-15(20)11-5-3-4-6-16-11/h3-9,19H,1-2H3,(H,18,20)

InChI Key

PNQBRMUCQLCIJQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01129620

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

301.3

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.252

Distribution Coefficient, logD

1.245

Water Solubility, LogSw

-1.98

Polar Surface Area

75.342

Acid Dissociation Constant (pKa)

9.24

Base Dissociation Constant (pKb)

1.80

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.30

1269-5590 in Drug Discovery

Included in Screening Libraries

Frequent Hitters Library (7624 compounds)

Glucocorticoid receptors Library (4806 compounds)

Carbonic Anhydrase II Library (4939 compounds)

Included in 1.7M Stock Database

Structure:
  • Pool
Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 1269-5590 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1269-5590?
Check Price and Availability of 1269-5590, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 1269-5590 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1269-5590
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1269-5590
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1269-5590 available by request