1434-0008 Screening compound: N'-(4-chlorophenyl)-2-hydroxy-2,2-bis(4-methoxyphenyl)acetohydrazide

1434-0008 Screening compound: N'-(4-chlorophenyl)-2-hydroxy-2,2-bis(4-methoxyphenyl)acetohydrazide
1434-0008 Screening compound: N'-(4-chlorophenyl)-2-hydroxy-2,2-bis(4-methoxyphenyl)acetohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 1434-0008
N'-(4-chlorophenyl)-2-hydroxy-2,2-bis(4-methoxyphenyl)acetohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1434-0008

Molecular Formula

C22H21ClN2O4 (C22 H21 ClN2 O4)

Compound Name

N'-(4-chlorophenyl)-2-hydroxy-2,2-bis(4-methoxyphenyl)acetohydrazide

IUPAC name

N'-(4-chlorophenyl)-2-hydroxy-22-bis(4-methoxyphenyl)acetohydrazide

SMILES

COc1ccc(C(C(NNc(cc2)ccc2Cl)=O)(c(cc2)ccc2OC)O)cc1

InChI

InChI=1S/C22H21ClN2O4/c1-28-19-11-3-15(4-12-19)22(27,16-5-13-20(29-2)14-6-16)21(26)25-24-18-9-7-17(23)8-10-18/h3-14,24,27H,1-2H3,(H,25,26)

InChI Key

KMJBBIVLRAFNHP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00507128

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.87

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.046

Distribution Coefficient, logD

4.038

Water Solubility, LogSw

-4.47

Polar Surface Area

67.140

Acid Dissociation Constant (pKa)

9.19

Base Dissociation Constant (pKb)

-1.67

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

1434-0008 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Frequent Hitters Library (7624 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
Structure:
  • Pool

References: we are preparing a list of scientific research reports with 1434-0008 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1434-0008?
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What is the minimum amount of 1434-0008 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1434-0008
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1434-0008
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1434-0008 available by request