1487-1655 Screening compound: (2E)-2-cyano-N-(2-methylphenyl)-3-[5-(4-methylphenyl)furan-2-yl]prop-2-enamide

1487-1655 Screening compound: (2E)-2-cyano-N-(2-methylphenyl)-3-[5-(4-methylphenyl)furan-2-yl]prop-2-enamide
1487-1655 Screening compound: (2E)-2-cyano-N-(2-methylphenyl)-3-[5-(4-methylphenyl)furan-2-yl]prop-2-enamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 1487-1655
(2E)-2-cyano-N-(2-methylphenyl)-3-[5-(4-methylphenyl)furan-2-yl]prop-2-enamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1487-1655

Molecular Formula

C22H18N2O2 (C22 H18 N2 O2)

Compound Name

(2E)-2-cyano-N-(2-methylphenyl)-3-[5-(4-methylphenyl)furan-2-yl]prop-2-enamide

IUPAC name

(2E)-2-cyano-N-(2-methylphenyl)-3-[5-(4-methylphenyl)furan-2-yl]prop-2-enamide

SMILES

Cc(cc1)ccc1-c1ccc(/C=C(/C(Nc2c(C)cccc2)=O)\C#N)o1

InChI

InChI=1S/C22H18N2O2/c1-15-7-9-17(10-8-15)21-12-11-19(26-21)13-18(14-23)22(25)24-20-6-4-3-5-16(20)2/h3-13H,1-2H3,(H,24,25)

InChI Key

HRAJHPQVKSUXEH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01531453

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

342.4

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.154

Distribution Coefficient, logD

5.151

Water Solubility, LogSw

-5.07

Polar Surface Area

47.258

Acid Dissociation Constant (pKa)

9.68

Base Dissociation Constant (pKb)

-0.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

1487-1655 in Drug Discovery

Included in Screening Libraries

Frequent Hitters Library (7624 compounds)

KRAS-Targeted Library (16000 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Structure:
  • Pool
  • Cyclic compounds
  • 3D
  • Fragments
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 1487-1655 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1487-1655?
Check Price and Availability of 1487-1655, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 1487-1655 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1487-1655
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1487-1655
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1487-1655 available by request