1488-0421 Screening compound: 4-fluoro-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]benzamide

1488-0421 Screening compound: 4-fluoro-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]benzamide
1488-0421 Screening compound: 4-fluoro-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 1488-0421
4-fluoro-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1488-0421

Molecular Formula

C17H13FN2OS (C17 H13 FN2 OS)

Compound Name

4-fluoro-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]benzamide

IUPAC name

4-fluoro-N-[4-(4-methylphenyl)-13-thiazol-2-yl]benzamide

SMILES

Cc(cc1)ccc1-c1csc(NC(c(cc2)ccc2F)=O)n1

InChI

InChI=1S/C17H13FN2OS/c1-11-2-4-12(5-3-11)15-10-22-17(19-15)20-16(21)13-6-8-14(18)9-7-13/h2-10H,1H3,(H,19,20,21)

InChI Key

ROEAQWBEUWNEKF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00988783

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

312.37

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

5.091

Distribution Coefficient, logD

5.085

Water Solubility, LogSw

-4.87

Polar Surface Area

33.104

Acid Dissociation Constant (pKa)

9.30

Base Dissociation Constant (pKb)

0.24

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.90

1488-0421 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Frequent Hitters Library (7624 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases
Structure:
  • Pool

References: we are preparing a list of scientific research reports with 1488-0421 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1488-0421?
Check Price and Availability of 1488-0421, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 1488-0421 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1488-0421
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1488-0421
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1488-0421 available by request