1488-2451 Screening compound: 6-bromo-2-[4-(2-methylphenyl)piperazin-1-yl]-4-phenylquinazoline

1488-2451 Screening compound: 6-bromo-2-[4-(2-methylphenyl)piperazin-1-yl]-4-phenylquinazoline
1488-2451 Screening compound: 6-bromo-2-[4-(2-methylphenyl)piperazin-1-yl]-4-phenylquinazoline alternative view

Chemical Structure Depiction of ChemDiv screening compound 1488-2451
6-bromo-2-[4-(2-methylphenyl)piperazin-1-yl]-4-phenylquinazoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1488-2451

Molecular Formula

C25H23BrN4 (C25 H23 BrN4)

Compound Name

6-bromo-2-[4-(2-methylphenyl)piperazin-1-yl]-4-phenylquinazoline

IUPAC name

6-bromo-2-[4-(2-methylphenyl)piperazin-1-yl]-4-phenylquinazoline

SMILES

Cc(cccc1)c1N(CC1)CCN1c1nc(-c2ccccc2)c(cc(cc2)Br)c2n1

InChI

InChI=1S/C25H23BrN4/c1-18-7-5-6-10-23(18)29-13-15-30(16-14-29)25-27-22-12-11-20(26)17-21(22)24(28-25)19-8-3-2-4-9-19/h2-12,17H,13-16H2,1H3

InChI Key

MWDGCBHEAMLCLM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01004672

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

459.39

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

7.026

Distribution Coefficient, logD

7.026

Water Solubility, LogSw

-5.99

Polar Surface Area

24.362

Acid Dissociation Constant (pKa)

20.75

Base Dissociation Constant (pKb)

3.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

1488-2451 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 1488-2451 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1488-2451?
Check Price and Availability of 1488-2451, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 1488-2451 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1488-2451
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1488-2451
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1488-2451 available by request