1495-0260 Screening compound: 1-(4-fluorobenzoyl)-3-(4-sulfamoylphenyl)thiourea

1495-0260 Screening compound: 1-(4-fluorobenzoyl)-3-(4-sulfamoylphenyl)thiourea
1495-0260 Screening compound: 1-(4-fluorobenzoyl)-3-(4-sulfamoylphenyl)thiourea alternative view

Chemical Structure Depiction of ChemDiv screening compound 1495-0260
1-(4-fluorobenzoyl)-3-(4-sulfamoylphenyl)thiourea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1495-0260

Molecular Formula

C14H12FN3O3S2 (C14 H12 FN3 O3 S2)

Compound Name

1-(4-fluorobenzoyl)-3-(4-sulfamoylphenyl)thiourea

IUPAC name

1-(4-fluorobenzoyl)-3-(4-sulfamoylphenyl)thiourea

SMILES

NS(c(cc1)ccc1NC(NC(c(cc1)ccc1F)=O)=S)(=O)=O

InChI

InChI=1S/C14H12FN3O3S2/c15-10-3-1-9(2-4-10)13(19)18-14(22)17-11-5-7-12(8-6-11)23(16,20)21/h1-8H,(H2,16,20,21)(H2,17,18,19,22)

InChI Key

FQHOKHIYKQCJEM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00696052

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

353.4

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.793

Distribution Coefficient, logD

1.787

Water Solubility, LogSw

-2.26

Polar Surface Area

83.843

Acid Dissociation Constant (pKa)

9.31

Base Dissociation Constant (pKb)

-4.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

1495-0260 in Drug Discovery

Included in Screening Libraries

Frequent Hitters Library (7624 compounds)

Covalent Inhibitors Library (7986 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Structure:
  • Pool
  • Cyclic compounds
  • 3D
  • Fragments
Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with 1495-0260 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1495-0260?
Check Price and Availability of 1495-0260, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 1495-0260 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1495-0260
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1495-0260
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1495-0260 available by request