1706-0189 Screening compound: 2-hydroxy-4-(4,5,6,7-tetrachloro-1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)benzoic acid

1706-0189 Screening compound: 2-hydroxy-4-(4,5,6,7-tetrachloro-1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)benzoic acid
1706-0189 Screening compound: 2-hydroxy-4-(4,5,6,7-tetrachloro-1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)benzoic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound 1706-0189
2-hydroxy-4-(4,5,6,7-tetrachloro-1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)benzoic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1706-0189

Molecular Formula

C15H5Cl4NO5 (C15 H5 Cl4 NO5)

Compound Name

2-hydroxy-4-(4,5,6,7-tetrachloro-1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)benzoic acid

IUPAC name

2-hydroxy-4-(4567-tetrachloro-13-dioxo-23-dihydro-1H-isoindol-2-yl)benzoic acid

SMILES

OC(c(ccc(N(C(c(c1c(c(Cl)c2Cl)Cl)c2Cl)=O)C1=O)c1)c1O)=O

InChI

InChI=1S/C15H5Cl4NO5/c16-9-7-8(10(17)12(19)11(9)18)14(23)20(13(7)22)4-1-2-5(15(24)25)6(21)3-4/h1-3,21H,(H,24,25)

InChI Key

ASCCVBAVMCLCRM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01046668

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.02

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.088

Distribution Coefficient, logD

1.059

Water Solubility, LogSw

-4.81

Polar Surface Area

73.836

Acid Dissociation Constant (pKa)

4.37

Base Dissociation Constant (pKb)

-11.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

1706-0189 in Drug Discovery

Included in Screening Libraries

Frequent Hitters Library (7624 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Receptor-type Protein Tyrosine Phosphatases Library (3746 compounds)

Included in 1.7M Stock Database

Structure:
  • Pool
Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
  • Cancer
  • Digestive system
  • Nervous system
  • Female
  • Metabolic
  • Endocrine
Targets:
  • Phosphatases
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 1706-0189 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1706-0189?
Check Price and Availability of 1706-0189, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 1706-0189 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1706-0189
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1706-0189
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1706-0189 available by request