1762-0453 Screening compound: N-(3-chloro-2-methylphenyl)-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
Chemical Structure Depiction of ChemDiv screening compound 1762-0453
N-(3-chloro-2-methylphenyl)-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
1762-0453
Molecular Formula
C19H12ClF3N4OS (C19 H12 ClF3 N4 OS)
Compound Name
N-(3-chloro-2-methylphenyl)-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
IUPAC name
N-(3-chloro-2-methylphenyl)-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[15-a]pyrimidine-2-carboxamide
SMILES
Cc(c(NC(c1nn2c(C(F)(F)F)cc(-c3cccs3)nc2c1)=O)ccc1)c1Cl
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
436.84
Hydrogen Bond Acceptors Count
4.00
Hydrogen Bond Donors Count
1.00
Rotatable Bond Count
5.00
Number of Nitrogen and Oxygen Atoms
5
Partition Coefficient, logP
5.659
Distribution Coefficient, logD
5.658
Water Solubility, LogSw
-5.99
Polar Surface Area
41.809
Acid Dissociation Constant (pKa)
10.08
Base Dissociation Constant (pKb)
-2.88
Number of Chiral Centers
0.00
Percent sp3 carbon bonding
10.50
1762-0453 in Drug Discovery
Included in Screening Libraries
Angiogenesis library (14822 compounds)
Antiviral Library (67538 compounds)
Frequent Hitters Library (7624 compounds)
Aurora A-B Kinases Targeted Library (9426 compounds)
Included in 1.7M Stock Database
- Cancer
- Antiviral
- Infections
- Immune system
- Cancer
- Digestive system
- Male
- Female
- Hemic and lymphatic
- Pool
- Kinases
References: we are preparing a list of scientific research reports with 1762-0453 chemical compound. It will be published here after verification.
Frequently Asked Questions
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Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)