1783-0083 Screening compound: (5E)-3-[3-(3,6-dichloro-9H-carbazol-9-yl)-2-hydroxypropyl]-5-{[4-(dimethylamino)phenyl]methylidene}-1,3-thiazolidine-2,4-dione

1783-0083 Screening compound: (5E)-3-[3-(3,6-dichloro-9H-carbazol-9-yl)-2-hydroxypropyl]-5-{[4-(dimethylamino)phenyl]methylidene}-1,3-thiazolidine-2,4-dione
1783-0083 Screening compound: (5E)-3-[3-(3,6-dichloro-9H-carbazol-9-yl)-2-hydroxypropyl]-5-{[4-(dimethylamino)phenyl]methylidene}-1,3-thiazolidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound 1783-0083
(5E)-3-[3-(3,6-dichloro-9H-carbazol-9-yl)-2-hydroxypropyl]-5-{[4-(dimethylamino)phenyl]methylidene}-1,3-thiazolidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1783-0083

Molecular Formula

C27H23Cl2N3O3S (C27 H23 Cl2 N3 O3 S)

Compound Name

(5E)-3-[3-(3,6-dichloro-9H-carbazol-9-yl)-2-hydroxypropyl]-5-{[4-(dimethylamino)phenyl]methylidene}-1,3-thiazolidine-2,4-dione

IUPAC name

(5E)-3-[3-(36-dichloro-9H-carbazol-9-yl)-2-hydroxypropyl]-5-{[4-(dimethylamino)phenyl]methylidene}-13-thiazolidine-24-dione

SMILES

CN(C)c1ccc(/C=C(\C(N2CC(Cn3c(ccc(Cl)c4)c4c4c3ccc(Cl)c4)O)=O)/SC2=O)cc1

InChI

InChI=1S/C27H23Cl2N3O3S/c1-30(2)19-7-3-16(4-8-19)11-25-26(34)32(27(35)36-25)15-20(33)14-31-23-9-5-17(28)12-21(23)22-13-18(29)6-10-24(22)31/h3-13,20,33H,14-15H2,1-2H3/t20-/m0/s1

InChI Key

GAPBNWWKAXXVHI-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD01046330

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

540.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.990

Distribution Coefficient, logD

6.990

Water Solubility, LogSw

-6.30

Polar Surface Area

49.995

Acid Dissociation Constant (pKa)

16.48

Base Dissociation Constant (pKb)

3.55

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

18.50

1783-0083 in Drug Discovery

Included in Screening Libraries

Frequent Hitters Library (7624 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Structure:
  • Pool
Therapeutical areas:
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds

References: we are preparing a list of scientific research reports with 1783-0083 chemical compound. It will be published here after verification.

Frequently Asked Questions

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What is the minimum amount of 1783-0083 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1783-0083
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1783-0083
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1783-0083 available by request