1805-1421 Screening compound: N'-[(E)-(2-HYDROXYPHENYL)METHYLIDENE]-2-[2-(PYRIDIN-2-YL)-1H-1,3-BENZODIAZOL-1-YL]ACETOHYDRAZIDE

1805-1421 Screening compound: N'-[(E)-(2-HYDROXYPHENYL)METHYLIDENE]-2-[2-(PYRIDIN-2-YL)-1H-1,3-BENZODIAZOL-1-YL]ACETOHYDRAZIDE
1805-1421 Screening compound: N'-[(E)-(2-HYDROXYPHENYL)METHYLIDENE]-2-[2-(PYRIDIN-2-YL)-1H-1,3-BENZODIAZOL-1-YL]ACETOHYDRAZIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound 1805-1421
N'-[(E)-(2-HYDROXYPHENYL)METHYLIDENE]-2-[2-(PYRIDIN-2-YL)-1H-1,3-BENZODIAZOL-1-YL]ACETOHYDRAZIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1805-1421

Molecular Formula

C21H17N5O2 (C21 H17 N5 O2)

Compound Name

N'-[(E)-(2-HYDROXYPHENYL)METHYLIDENE]-2-[2-(PYRIDIN-2-YL)-1H-1,3-BENZODIAZOL-1-YL]ACETOHYDRAZIDE

IUPAC name

N'-[(E)-(2-hydroxyphenyl)methylidene]-2-[2-(pyridin-2-yl)-1H-13-benzodiazol-1-yl]acetohydrazide

SMILES

Oc1c(/C=N/NC(Cn2c(-c3ncccc3)nc3c2cccc3)=O)cccc1

InChI

InChI=1S/C21H17N5O2/c27-19-11-4-1-7-15(19)13-23-25-20(28)14-26-18-10-3-2-8-16(18)24-21(26)17-9-5-6-12-22-17/h1-13,27H,14H2,(H,25,28)

InChI Key

CTPGTJXBWHHDHE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01147304

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

371.4

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.476

Distribution Coefficient, logD

3.474

Water Solubility, LogSw

-3.06

Polar Surface Area

70.865

Acid Dissociation Constant (pKa)

9.91

Base Dissociation Constant (pKb)

3.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.80

1805-1421 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 1805-1421 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1805-1421?
Check Price and Availability of 1805-1421, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 1805-1421 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1805-1421
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1805-1421
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1805-1421 available by request