1814-2237 Screening compound: N'-[(E)-amino[7-(diethylamino)-2-oxo-2H-chromen-3-yl]methylidene]-4-nitrobenzohydrazide

1814-2237 Screening compound: N'-[(E)-amino[7-(diethylamino)-2-oxo-2H-chromen-3-yl]methylidene]-4-nitrobenzohydrazide
1814-2237 Screening compound: N'-[(E)-amino[7-(diethylamino)-2-oxo-2H-chromen-3-yl]methylidene]-4-nitrobenzohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 1814-2237
N'-[(E)-amino[7-(diethylamino)-2-oxo-2H-chromen-3-yl]methylidene]-4-nitrobenzohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1814-2237

Molecular Formula

C21H21N5O5 (C21 H21 N5 O5)

Compound Name

N'-[(E)-amino[7-(diethylamino)-2-oxo-2H-chromen-3-yl]methylidene]-4-nitrobenzohydrazide

IUPAC name

N'-[(E)-amino[7-(diethylamino)-2-oxo-2H-chromen-3-yl]methylidene]-4-nitrobenzohydrazide

SMILES

CCN(CC)c(cc1)cc(O2)c1C=C(/C(/N)=N\NC(c(cc1)ccc1[N+]([O-])=O)=O)C2=O

InChI

InChI=1S/C21H21N5O5/c1-3-25(4-2)16-10-7-14-11-17(21(28)31-18(14)12-16)19(22)23-24-20(27)13-5-8-15(9-6-13)26(29)30/h5-12H,3-4H2,1-2H3,(H2,22,23)(H,24,27)

InChI Key

AKASJXYPVMXHTB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01839281

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

423.43

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.934

Distribution Coefficient, logD

1.442

Water Solubility, LogSw

-3.56

Polar Surface Area

112.443

Acid Dissociation Constant (pKa)

5.92

Base Dissociation Constant (pKb)

3.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

1814-2237 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 1814-2237 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1814-2237?
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What is the minimum amount of 1814-2237 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1814-2237
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1814-2237
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1814-2237 available by request