1927-8386 Screening compound: (Z)-N'-{[(3E)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]amino}-N-(pyridin-2-yl)pyridine-2-carboximidamide

1927-8386 Screening compound: (Z)-N'-{[(3E)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]amino}-N-(pyridin-2-yl)pyridine-2-carboximidamide
1927-8386 Screening compound: (Z)-N'-{[(3E)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]amino}-N-(pyridin-2-yl)pyridine-2-carboximidamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 1927-8386
(Z)-N'-{[(3E)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]amino}-N-(pyridin-2-yl)pyridine-2-carboximidamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1927-8386

Molecular Formula

C19H13FN6O (C19 H13 FN6 O)

Compound Name

(Z)-N'-{[(3E)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]amino}-N-(pyridin-2-yl)pyridine-2-carboximidamide

IUPAC name

(Z)-N'-{[(3E)-5-fluoro-2-oxo-23-dihydro-1H-indol-3-ylidene]amino}-N-(pyridin-2-yl)pyridine-2-carboximidamide

SMILES

O=C1Nc(ccc(F)c2)c2/C1=N\N=C(\c1ncccc1)/Nc1ncccc1

InChI

InChI=1S/C19H13FN6O/c20-12-7-8-14-13(11-12)17(19(27)23-14)25-26-18(15-5-1-3-9-21-15)24-16-6-2-4-10-22-16/h1-11H,(H,22,24,26)(H,23,25,27)

InChI Key

GBQFAJHUXNDBPM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01247279

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

360.35

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.165

Distribution Coefficient, logD

3.153

Water Solubility, LogSw

-3.61

Polar Surface Area

70.948

Acid Dissociation Constant (pKa)

8.94

Base Dissociation Constant (pKb)

3.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

1927-8386 in Drug Discovery

Included in Screening Libraries

Frequent Hitters Library (7624 compounds)

Akt-Targeted Library (14764 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Structure:
  • Pool
Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with 1927-8386 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1927-8386?
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What is the minimum amount of 1927-8386 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1927-8386
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1927-8386
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1927-8386 available by request