1937-0354 Screening compound: N-{5-[2-(4-chlorobenzenesulfonyl)ethyl]-1,3,4-thiadiazol-2-yl}-3-methoxybenzamide

1937-0354 Screening compound: N-{5-[2-(4-chlorobenzenesulfonyl)ethyl]-1,3,4-thiadiazol-2-yl}-3-methoxybenzamide
1937-0354 Screening compound: N-{5-[2-(4-chlorobenzenesulfonyl)ethyl]-1,3,4-thiadiazol-2-yl}-3-methoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 1937-0354
N-{5-[2-(4-chlorobenzenesulfonyl)ethyl]-1,3,4-thiadiazol-2-yl}-3-methoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

1937-0354

Molecular Formula

C18H16ClN3O4S2 (C18 H16 ClN3 O4 S2)

Compound Name

N-{5-[2-(4-chlorobenzenesulfonyl)ethyl]-1,3,4-thiadiazol-2-yl}-3-methoxybenzamide

IUPAC name

N-{5-[2-(4-chlorobenzenesulfonyl)ethyl]-134-thiadiazol-2-yl}-3-methoxybenzamide

SMILES

COc1cccc(C(Nc2nnc(CCS(c(cc3)ccc3Cl)(=O)=O)s2)=O)c1

InChI

InChI=1S/C18H16ClN3O4S2/c1-26-14-4-2-3-12(11-14)17(23)20-18-22-21-16(27-18)9-10-28(24,25)15-7-5-13(19)6-8-15/h2-8,11H,9-10H2,1H3,(H,20,22,23)

InChI Key

LPRKIDNBBYBTBK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01046505

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.93

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.659

Distribution Coefficient, logD

3.335

Water Solubility, LogSw

-4.32

Polar Surface Area

83.678

Acid Dissociation Constant (pKa)

7.36

Base Dissociation Constant (pKb)

-3.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

1937-0354 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with 1937-0354 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 1937-0354?
Check Price and Availability of 1937-0354, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 1937-0354 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 1937-0354
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 1937-0354
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 1937-0354 available by request