2043-8301 Screening compound: N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide

2043-8301 Screening compound: N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide
2043-8301 Screening compound: N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 2043-8301
N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2043-8301

Molecular Formula

C20H13FN2OS (C20 H13 FN2 OS)

Compound Name

N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide

IUPAC name

N-(4-fluorophenyl)-2-(thiophen-2-yl)quinoline-4-carboxamide

SMILES

O=C(c1cc(-c2cccs2)nc2ccccc12)Nc(cc1)ccc1F

InChI

InChI=1S/C20H13FN2OS/c21-13-7-9-14(10-8-13)22-20(24)16-12-18(19-6-3-11-25-19)23-17-5-2-1-4-15(16)17/h1-12H,(H,22,24)

InChI Key

QSOYDLNLYHOQPB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01106792

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

348.4

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

5.229

Distribution Coefficient, logD

5.229

Water Solubility, LogSw

-5.61

Polar Surface Area

32.407

Acid Dissociation Constant (pKa)

11.09

Base Dissociation Constant (pKb)

0.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

2043-8301 in Drug Discovery

Included in Screening Libraries

Antiviral Annotated Library (21441 compounds)

Antiviral HBV Library (10007 compounds)

GPCR Targeted Library (31838 compounds)

Human Kinases Annotated Library (2415 compounds)

Human Proteases Annotated Library (2868 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 2043-8301 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2043-8301?
Check Price and Availability of 2043-8301, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 2043-8301 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2043-8301
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2043-8301
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2043-8301 available by request