2144-0800 Screening compound: N5-(3-chloro-4-methylphenyl)-N6-(2-methoxyphenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine

2144-0800 Screening compound: N5-(3-chloro-4-methylphenyl)-N6-(2-methoxyphenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine
2144-0800 Screening compound: N5-(3-chloro-4-methylphenyl)-N6-(2-methoxyphenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine alternative view

Chemical Structure Depiction of ChemDiv screening compound 2144-0800
N5-(3-chloro-4-methylphenyl)-N6-(2-methoxyphenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2144-0800

Molecular Formula

C18H15ClN6O2 (C18 H15 ClN6 O2)

Compound Name

N5-(3-chloro-4-methylphenyl)-N6-(2-methoxyphenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine

IUPAC name

N5-(3-chloro-4-methylphenyl)-N6-(2-methoxyphenyl)-[125]oxadiazolo[34-b]pyrazine-56-diamine

SMILES

Cc(ccc(Nc1nc2nonc2nc1Nc(cccc1)c1OC)c1)c1Cl

InChI

InChI=1S/C18H15ClN6O2/c1-10-7-8-11(9-12(10)19)20-15-16(23-18-17(22-15)24-27-25-18)21-13-5-3-4-6-14(13)26-2/h3-9H,1-2H3,(H,20,22,24)(H,21,23,25)

InChI Key

VAAVHUIQWSZCPT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00632612

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.81

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.918

Distribution Coefficient, logD

5.918

Water Solubility, LogSw

-6.17

Polar Surface Area

81.479

Acid Dissociation Constant (pKa)

15.15

Base Dissociation Constant (pKb)

-1.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

2144-0800 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 2144-0800 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2144-0800?
Check Price and Availability of 2144-0800, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 2144-0800 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2144-0800
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2144-0800
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2144-0800 available by request