2214-0008 Screening compound: 2-[4-(6-bromo-4-phenylquinolin-2-yl)phenoxy]-N'-[(E)-(2,4-dimethoxyphenyl)methylidene]acetohydrazide

2214-0008 Screening compound: 2-[4-(6-bromo-4-phenylquinolin-2-yl)phenoxy]-N'-[(E)-(2,4-dimethoxyphenyl)methylidene]acetohydrazide
2214-0008 Screening compound: 2-[4-(6-bromo-4-phenylquinolin-2-yl)phenoxy]-N'-[(E)-(2,4-dimethoxyphenyl)methylidene]acetohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 2214-0008
2-[4-(6-bromo-4-phenylquinolin-2-yl)phenoxy]-N'-[(E)-(2,4-dimethoxyphenyl)methylidene]acetohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2214-0008

Molecular Formula

C32H26BrN3O4 (C32 H26 BrN3 O4)

Compound Name

2-[4-(6-bromo-4-phenylquinolin-2-yl)phenoxy]-N'-[(E)-(2,4-dimethoxyphenyl)methylidene]acetohydrazide

IUPAC name

2-[4-(6-bromo-4-phenylquinolin-2-yl)phenoxy]-N'-[(E)-(24-dimethoxyphenyl)methylidene]acetohydrazide

SMILES

COc1cc(OC)c(/C=N/NC(COc(cc2)ccc2-c2cc(-c3ccccc3)c(cc(cc3)Br)c3n2)=O)cc1

InChI

InChI=1S/C32H26BrN3O4/c1-38-26-14-10-23(31(17-26)39-2)19-34-36-32(37)20-40-25-12-8-22(9-13-25)30-18-27(21-6-4-3-5-7-21)28-16-24(33)11-15-29(28)35-30/h3-19H,20H2,1-2H3,(H,36,37)

InChI Key

JQVWHWCFGQXWGZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01535104

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

596.48

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

8.059

Distribution Coefficient, logD

8.057

Water Solubility, LogSw

-5.91

Polar Surface Area

65.802

Acid Dissociation Constant (pKa)

11.17

Base Dissociation Constant (pKb)

5.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.40

2214-0008 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 2214-0008 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2214-0008?
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What is the minimum amount of 2214-0008 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2214-0008
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2214-0008
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2214-0008 available by request