2235-0147 Screening compound: N'-[(1E)-1-(4-methylphenyl)ethylidene]-2-[2-(pyridin-2-yl)-1H-1,3-benzodiazol-1-yl]acetohydrazide

2235-0147 Screening compound: N'-[(1E)-1-(4-methylphenyl)ethylidene]-2-[2-(pyridin-2-yl)-1H-1,3-benzodiazol-1-yl]acetohydrazide
2235-0147 Screening compound: N'-[(1E)-1-(4-methylphenyl)ethylidene]-2-[2-(pyridin-2-yl)-1H-1,3-benzodiazol-1-yl]acetohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 2235-0147
N'-[(1E)-1-(4-methylphenyl)ethylidene]-2-[2-(pyridin-2-yl)-1H-1,3-benzodiazol-1-yl]acetohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2235-0147

Molecular Formula

C23H21N5O (C23 H21 N5 O)

Compound Name

N'-[(1E)-1-(4-methylphenyl)ethylidene]-2-[2-(pyridin-2-yl)-1H-1,3-benzodiazol-1-yl]acetohydrazide

IUPAC name

N'-[(1E)-1-(4-methylphenyl)ethylidene]-2-[2-(pyridin-2-yl)-1H-13-benzodiazol-1-yl]acetohydrazide

SMILES

C/C(/c1ccc(C)cc1)=N\NC(Cn1c(-c2ncccc2)nc2c1cccc2)=O

InChI

InChI=1S/C23H21N5O/c1-16-10-12-18(13-11-16)17(2)26-27-22(29)15-28-21-9-4-3-7-19(21)25-23(28)20-8-5-6-14-24-20/h3-14H,15H2,1-2H3,(H,27,29)

InChI Key

KVRMEVFTWGGQRQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01535127

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

383.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.134

Distribution Coefficient, logD

4.133

Water Solubility, LogSw

-4.19

Polar Surface Area

53.605

Acid Dissociation Constant (pKa)

10.09

Base Dissociation Constant (pKb)

3.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

2235-0147 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 2235-0147 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2235-0147?
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What is the minimum amount of 2235-0147 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2235-0147
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2235-0147
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2235-0147 available by request