2290-1664 Screening compound: (2E)-N-(8-nitro-2-oxo-2H-chromen-3-yl)-3-phenylprop-2-enamide

2290-1664 Screening compound: (2E)-N-(8-nitro-2-oxo-2H-chromen-3-yl)-3-phenylprop-2-enamide
2290-1664 Screening compound: (2E)-N-(8-nitro-2-oxo-2H-chromen-3-yl)-3-phenylprop-2-enamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 2290-1664
(2E)-N-(8-nitro-2-oxo-2H-chromen-3-yl)-3-phenylprop-2-enamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2290-1664

Molecular Formula

C18H12N2O5 (C18 H12 N2 O5)

Compound Name

(2E)-N-(8-nitro-2-oxo-2H-chromen-3-yl)-3-phenylprop-2-enamide

IUPAC name

(2E)-N-(8-nitro-2-oxo-2H-chromen-3-yl)-3-phenylprop-2-enamide

SMILES

[O-][N+](c(cccc1C=C2NC(/C=C/c3ccccc3)=O)c1OC2=O)=O

InChI

InChI=1S/C18H12N2O5/c21-16(10-9-12-5-2-1-3-6-12)19-14-11-13-7-4-8-15(20(23)24)17(13)25-18(14)22/h1-11H,(H,19,21)

InChI Key

RPXZFKUWONLCNP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01535216

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

336.3

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.656

Distribution Coefficient, logD

3.578

Water Solubility, LogSw

-4.19

Polar Surface Area

77.766

Acid Dissociation Constant (pKa)

10.68

Base Dissociation Constant (pKb)

6.69

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

2290-1664 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Kinases
Structure:
  • Cyclic compounds
  • 3D
  • Fragments
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 2290-1664 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2290-1664?
Check Price and Availability of 2290-1664, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 2290-1664 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2290-1664
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2290-1664
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2290-1664 available by request