2297-0105 Screening compound: 6-bromo-3-[5-(4-bromophenyl)-1-(2-chlorobenzoyl)-4,5-dihydro-1H-pyrazol-3-yl]-4-phenyl-1,2-dihydroquinolin-2-one

2297-0105 Screening compound: 6-bromo-3-[5-(4-bromophenyl)-1-(2-chlorobenzoyl)-4,5-dihydro-1H-pyrazol-3-yl]-4-phenyl-1,2-dihydroquinolin-2-one
2297-0105 Screening compound: 6-bromo-3-[5-(4-bromophenyl)-1-(2-chlorobenzoyl)-4,5-dihydro-1H-pyrazol-3-yl]-4-phenyl-1,2-dihydroquinolin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 2297-0105
6-bromo-3-[5-(4-bromophenyl)-1-(2-chlorobenzoyl)-4,5-dihydro-1H-pyrazol-3-yl]-4-phenyl-1,2-dihydroquinolin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2297-0105

Molecular Formula

C31H20Br2ClN3O2 (C31 H20 Br2 ClN3 O2)

Compound Name

6-bromo-3-[5-(4-bromophenyl)-1-(2-chlorobenzoyl)-4,5-dihydro-1H-pyrazol-3-yl]-4-phenyl-1,2-dihydroquinolin-2-one

IUPAC name

6-bromo-3-[5-(4-bromophenyl)-1-(2-chlorobenzoyl)-45-dihydro-1H-pyrazol-3-yl]-4-phenyl-12-dihydroquinolin-2-one

SMILES

O=C(c(cccc1)c1Cl)N(C(C1)c(cc2)ccc2Br)N=C1C1=C(c2ccccc2)c(cc(cc2)Br)c2NC1=O

InChI

InChI=1S/C31H20Br2ClN3O2/c32-20-12-10-18(11-13-20)27-17-26(36-37(27)31(39)22-8-4-5-9-24(22)34)29-28(19-6-2-1-3-7-19)23-16-21(33)14-15-25(23)35-30(29)38/h1-16,27H,17H2,(H,35,38)/t27-/m1/s1

InChI Key

JUKKQEHPGDAHBP-HHHXNRCGSA-N

MDL Number (MFCD)

MFCD01931605

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

661.78

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

8.154

Distribution Coefficient, logD

8.117

Water Solubility, LogSw

-6.52

Polar Surface Area

51.721

Acid Dissociation Constant (pKa)

8.44

Base Dissociation Constant (pKb)

-4.66

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

6.50

2297-0105 in Drug Discovery

Included in Screening Libraries

MCL1 Targeted Library (12200 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic

References: we are preparing a list of scientific research reports with 2297-0105 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2297-0105?
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What is the minimum amount of 2297-0105 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2297-0105
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2297-0105
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2297-0105 available by request