2374-0022 Screening compound: 1-[4-(2,4-dichlorophenyl)-3H,3aH,4H,5H,9bH-cyclopenta[c]quinolin-8-yl]ethan-1-one

2374-0022 Screening compound: 1-[4-(2,4-dichlorophenyl)-3H,3aH,4H,5H,9bH-cyclopenta[c]quinolin-8-yl]ethan-1-one
2374-0022 Screening compound: 1-[4-(2,4-dichlorophenyl)-3H,3aH,4H,5H,9bH-cyclopenta[c]quinolin-8-yl]ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 2374-0022
1-[4-(2,4-dichlorophenyl)-3H,3aH,4H,5H,9bH-cyclopenta[c]quinolin-8-yl]ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2374-0022

Molecular Formula

C20H17Cl2NO (C20 H17 Cl2 NO)

Compound Name

1-[4-(2,4-dichlorophenyl)-3H,3aH,4H,5H,9bH-cyclopenta[c]quinolin-8-yl]ethan-1-one

IUPAC name

1-[4-(24-dichlorophenyl)-3H3aH4H5H9bH-cyclopenta[c]quinolin-8-yl]ethan-1-one

SMILES

CC(c(cc1)cc(C2C=CCC22)c1NC2c(ccc(Cl)c1)c1Cl)=O

InChI

InChI=1S/C20H17Cl2NO/c1-11(24)12-5-8-19-17(9-12)14-3-2-4-15(14)20(23-19)16-7-6-13(21)10-18(16)22/h2-3,5-10,14-15,20,23H,4H2,1H3

InChI Key

FHGJPIGQRQJWHG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01593505

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

358.27

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

2

Partition Coefficient, logP

5.831

Distribution Coefficient, logD

5.831

Water Solubility, LogSw

-6.02

Polar Surface Area

26.148

Acid Dissociation Constant (pKa)

16.95

Base Dissociation Constant (pKb)

-4.11

Number of Chiral Centers

3.00

Percent sp3 carbon bonding

25.00

2374-0022 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

BRD4 Targeted Library (4534 compounds)

KRAS-Targeted Library (16000 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Others
  • Kinases

References: we are preparing a list of scientific research reports with 2374-0022 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2374-0022?
Check Price and Availability of 2374-0022, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 2374-0022 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2374-0022
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2374-0022
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2374-0022 available by request