2423-4507 Screening compound: N'-[(E)-(2-hydroxy-3-methoxyphenyl)methylidene]-3-(naphthalen-2-yl)-1H-pyrazole-5-carbohydrazide

2423-4507 Screening compound: N'-[(E)-(2-hydroxy-3-methoxyphenyl)methylidene]-3-(naphthalen-2-yl)-1H-pyrazole-5-carbohydrazide
2423-4507 Screening compound: N'-[(E)-(2-hydroxy-3-methoxyphenyl)methylidene]-3-(naphthalen-2-yl)-1H-pyrazole-5-carbohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 2423-4507
N'-[(E)-(2-hydroxy-3-methoxyphenyl)methylidene]-3-(naphthalen-2-yl)-1H-pyrazole-5-carbohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

2423-4507

Molecular Formula

C22H18N4O3 (C22 H18 N4 O3)

Compound Name

N'-[(E)-(2-hydroxy-3-methoxyphenyl)methylidene]-3-(naphthalen-2-yl)-1H-pyrazole-5-carbohydrazide

IUPAC name

N'-[(E)-(2-hydroxy-3-methoxyphenyl)methylidene]-3-(naphthalen-2-yl)-1H-pyrazole-5-carbohydrazide

SMILES

COc1cccc(/C=N/NC(c2cc(-c3cc4ccccc4cc3)n[nH]2)=O)c1O

InChI

InChI=1S/C22H18N4O3/c1-29-20-8-4-7-17(21(20)27)13-23-26-22(28)19-12-18(24-25-19)16-10-9-14-5-2-3-6-15(14)11-16/h2-13,27H,1H3,(H,24,25)(H,26,28)

InChI Key

USVQPRHWEJENHB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01842052

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.41

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.881

Distribution Coefficient, logD

4.878

Water Solubility, LogSw

-5.28

Polar Surface Area

80.882

Acid Dissociation Constant (pKa)

9.59

Base Dissociation Constant (pKb)

0.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.50

2423-4507 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 2423-4507 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 2423-4507?
Check Price and Availability of 2423-4507, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 2423-4507 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 2423-4507
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 2423-4507
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 2423-4507 available by request