3209-0219 Screening compound: 1-[5-(4-chlorophenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]-4-(diphenylmethyl)piperazine

3209-0219 Screening compound: 1-[5-(4-chlorophenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]-4-(diphenylmethyl)piperazine
3209-0219 Screening compound: 1-[5-(4-chlorophenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]-4-(diphenylmethyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound 3209-0219
1-[5-(4-chlorophenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]-4-(diphenylmethyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

3209-0219

Molecular Formula

C32H27ClF3N5O (C32 H27 ClF3 N5 O)

Compound Name

1-[5-(4-chlorophenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]-4-(diphenylmethyl)piperazine

IUPAC name

1-[5-(4-chlorophenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[15-a]pyrimidine-3-carbonyl]-4-(diphenylmethyl)piperazine

SMILES

Cc1nn2c(C(F)(F)F)cc(-c(cc3)ccc3Cl)nc2c1C(N(CC1)CCN1C(c1ccccc1)c1ccccc1)=O

InChI

InChI=1S/C32H27ClF3N5O/c1-21-28(30-37-26(22-12-14-25(33)15-13-22)20-27(32(34,35)36)41(30)38-21)31(42)40-18-16-39(17-19-40)29(23-8-4-2-5-9-23)24-10-6-3-7-11-24/h2-15,20,29H,16-19H2,1H3

InChI Key

PNOPUCHNGQAJCW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01528536

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

590.05

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.896

Distribution Coefficient, logD

6.895

Water Solubility, LogSw

-6.41

Polar Surface Area

38.730

Acid Dissociation Constant (pKa)

25.05

Base Dissociation Constant (pKb)

4.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.90

3209-0219 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

DGK Inhibitors Library (10558 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
Targets:
  • Kinases
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with 3209-0219 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 3209-0219?
Check Price and Availability of 3209-0219, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 3209-0219 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 3209-0219
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 3209-0219
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 3209-0219 available by request