3277-0440 Screening compound: N5-(2,3-dimethylphenyl)-N6-(4-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine

3277-0440 Screening compound: N5-(2,3-dimethylphenyl)-N6-(4-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine
3277-0440 Screening compound: N5-(2,3-dimethylphenyl)-N6-(4-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine alternative view

Chemical Structure Depiction of ChemDiv screening compound 3277-0440
N5-(2,3-dimethylphenyl)-N6-(4-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

3277-0440

Molecular Formula

C18H15FN6O (C18 H15 FN6 O)

Compound Name

N5-(2,3-dimethylphenyl)-N6-(4-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine

IUPAC name

N5-(23-dimethylphenyl)-N6-(4-fluorophenyl)-[125]oxadiazolo[34-b]pyrazine-56-diamine

SMILES

Cc1cccc(Nc2nc3nonc3nc2Nc(cc2)ccc2F)c1C

InChI

InChI=1S/C18H15FN6O/c1-10-4-3-5-14(11(10)2)21-16-15(20-13-8-6-12(19)7-9-13)22-17-18(23-16)25-26-24-17/h3-9H,1-2H3,(H,20,22,24)(H,21,23,25)

InChI Key

JDUIPEOFLFWSST-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00815615

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

350.36

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.434

Distribution Coefficient, logD

5.434

Water Solubility, LogSw

-5.60

Polar Surface Area

73.848

Acid Dissociation Constant (pKa)

15.77

Base Dissociation Constant (pKb)

-2.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

3277-0440 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 3277-0440 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 3277-0440?
Check Price and Availability of 3277-0440, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 3277-0440 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 3277-0440
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 3277-0440
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 3277-0440 available by request