3448-4661 Screening compound: 5-(3,4-dimethoxyphenyl)-1-phenyl-3-(phenylamino)-2,5-dihydro-1H-pyrrol-2-one

3448-4661 Screening compound: 5-(3,4-dimethoxyphenyl)-1-phenyl-3-(phenylamino)-2,5-dihydro-1H-pyrrol-2-one
3448-4661 Screening compound: 5-(3,4-dimethoxyphenyl)-1-phenyl-3-(phenylamino)-2,5-dihydro-1H-pyrrol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 3448-4661
5-(3,4-dimethoxyphenyl)-1-phenyl-3-(phenylamino)-2,5-dihydro-1H-pyrrol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

3448-4661

Molecular Formula

C24H22N2O3 (C24 H22 N2 O3)

Compound Name

5-(3,4-dimethoxyphenyl)-1-phenyl-3-(phenylamino)-2,5-dihydro-1H-pyrrol-2-one

IUPAC name

5-(34-dimethoxyphenyl)-1-phenyl-3-(phenylamino)-25-dihydro-1H-pyrrol-2-one

SMILES

COc(ccc(C(C=C(C1=O)Nc2ccccc2)N1c1ccccc1)c1)c1OC

InChI

InChI=1S/C24H22N2O3/c1-28-22-14-13-17(15-23(22)29-2)21-16-20(25-18-9-5-3-6-10-18)24(27)26(21)19-11-7-4-8-12-19/h3-16,21,25H,1-2H3/t21-/m1/s1

InChI Key

SMCHVNBDEYDAJA-OAQYLSRUSA-N

MDL Number (MFCD)

MFCD01629969

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.45

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.141

Distribution Coefficient, logD

4.141

Water Solubility, LogSw

-4.37

Polar Surface Area

40.990

Acid Dissociation Constant (pKa)

13.88

Base Dissociation Constant (pKb)

-5.54

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

12.50

3448-4661 in Drug Discovery

Included in Screening Libraries

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with 3448-4661 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 3448-4661?
Check Price and Availability of 3448-4661, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 3448-4661 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 3448-4661
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 3448-4661
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 3448-4661 available by request