4215-0272 Screening compound: N2,N4-bis(3-chlorophenyl)-5-fluoropyrimidine-2,4-diamine

4215-0272 Screening compound: N2,N4-bis(3-chlorophenyl)-5-fluoropyrimidine-2,4-diamine
4215-0272 Screening compound: N2,N4-bis(3-chlorophenyl)-5-fluoropyrimidine-2,4-diamine alternative view

Chemical Structure Depiction of ChemDiv screening compound 4215-0272
N2,N4-bis(3-chlorophenyl)-5-fluoropyrimidine-2,4-diamine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4215-0272

Molecular Formula

C16H11Cl2FN4 (C16 H11 Cl2 FN4)

Compound Name

N2,N4-bis(3-chlorophenyl)-5-fluoropyrimidine-2,4-diamine

IUPAC name

N2N4-bis(3-chlorophenyl)-5-fluoropyrimidine-24-diamine

SMILES

Fc1c(Nc2cc(Cl)ccc2)nc(Nc2cccc(Cl)c2)nc1

InChI

InChI=1S/C16H11Cl2FN4/c17-10-3-1-5-12(7-10)21-15-14(19)9-20-16(23-15)22-13-6-2-4-11(18)8-13/h1-9H,(H2,20,21,22,23)

InChI Key

RUPMYJYSOQCMBT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00400730

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

349.19

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.845

Distribution Coefficient, logD

5.839

Water Solubility, LogSw

-6.27

Polar Surface Area

38.930

Acid Dissociation Constant (pKa)

15.50

Base Dissociation Constant (pKb)

5.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

4215-0272 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Antiviral Annotated Library (21441 compounds)

CNS Targets (44014 compounds)

Human Kinases Annotated Library (2415 compounds)

Proline Kinase Library (2105 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Nervous system
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with 4215-0272 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4215-0272?
Check Price and Availability of 4215-0272, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4215-0272 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4215-0272
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4215-0272
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4215-0272 available by request