4281-0266 Screening compound: N-(4-bromophenyl)-2-{3H-imidazo[4,5-b]pyridin-2-ylsulfanyl}acetamide

4281-0266 Screening compound: N-(4-bromophenyl)-2-{3H-imidazo[4,5-b]pyridin-2-ylsulfanyl}acetamide
4281-0266 Screening compound: N-(4-bromophenyl)-2-{3H-imidazo[4,5-b]pyridin-2-ylsulfanyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 4281-0266
N-(4-bromophenyl)-2-{3H-imidazo[4,5-b]pyridin-2-ylsulfanyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4281-0266

Molecular Formula

C14H11BrN4OS (C14 H11 BrN4 OS)

Compound Name

N-(4-bromophenyl)-2-{3H-imidazo[4,5-b]pyridin-2-ylsulfanyl}acetamide

IUPAC name

N-(4-bromophenyl)-2-{3H-imidazo[45-b]pyridin-2-ylsulfanyl}acetamide

SMILES

O=C(CSc([nH]1)nc2c1nccc2)Nc(cc1)ccc1Br

InChI

InChI=1S/C14H11BrN4OS/c15-9-3-5-10(6-4-9)17-12(20)8-21-14-18-11-2-1-7-16-13(11)19-14/h1-7H,8H2,(H,17,20)(H,16,18,19)

InChI Key

VQEQZCNYHDTJTI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03082581

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

363.24

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.809

Distribution Coefficient, logD

2.801

Water Solubility, LogSw

-3.33

Polar Surface Area

51.503

Acid Dissociation Constant (pKa)

9.16

Base Dissociation Constant (pKb)

3.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

7.10

4281-0266 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

NOTUM (Wnt signaling) Library (3881 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with 4281-0266 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4281-0266?
Check Price and Availability of 4281-0266, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4281-0266 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4281-0266
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4281-0266
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4281-0266 available by request