4286-0145 Screening compound: (3Z)-3-[(4-hydroxyphenyl)methylidene]pyrrolidine-2,4-dione

4286-0145 Screening compound: (3Z)-3-[(4-hydroxyphenyl)methylidene]pyrrolidine-2,4-dione
4286-0145 Screening compound: (3Z)-3-[(4-hydroxyphenyl)methylidene]pyrrolidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound 4286-0145
(3Z)-3-[(4-hydroxyphenyl)methylidene]pyrrolidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4286-0145

Molecular Formula

C11H9NO3 (C11 H9 NO3)

Compound Name

(3Z)-3-[(4-hydroxyphenyl)methylidene]pyrrolidine-2,4-dione

IUPAC name

(3Z)-3-[(4-hydroxyphenyl)methylidene]pyrrolidine-24-dione

SMILES

Oc1ccc(/C=C(/C(CN2)=O)\C2=O)cc1

InChI

InChI=1S/C11H9NO3/c13-8-3-1-7(2-4-8)5-9-10(14)6-12-11(9)15/h1-5,13H,6H2,(H,12,15)

InChI Key

PMYPUHRSXLKVBB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03016586

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

203.2

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

0.510

Distribution Coefficient, logD

0.508

Water Solubility, LogSw

-1.71

Polar Surface Area

56.401

Acid Dissociation Constant (pKa)

9.67

Base Dissociation Constant (pKb)

-2.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

4286-0145 in Drug Discovery

Included in Screening Libraries

CORONAVIRUS Library (20774 compounds)

Dark Chemical Matter Library (18430 compounds)

PLpro Library (6343 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Receptor-type Protein Tyrosine Phosphatases Library (3746 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Nervous system
  • Female
  • Metabolic
  • Endocrine
Structure:
  • Pool
Targets:
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 4286-0145 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4286-0145?
Check Price and Availability of 4286-0145, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4286-0145 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4286-0145
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4286-0145
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4286-0145 available by request