4290-0148 Screening compound: 4-[4-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)-6-METHYL-5-NITROPYRIMIDIN-2-YL]MORPHOLINE

4290-0148 Screening compound: 4-[4-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)-6-METHYL-5-NITROPYRIMIDIN-2-YL]MORPHOLINE
4290-0148 Screening compound: 4-[4-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)-6-METHYL-5-NITROPYRIMIDIN-2-YL]MORPHOLINE alternative view

Chemical Structure Depiction of ChemDiv screening compound 4290-0148
4-[4-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)-6-METHYL-5-NITROPYRIMIDIN-2-YL]MORPHOLINE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4290-0148

Molecular Formula

C14H18N6O3 (C14 H18 N6 O3)

Compound Name

4-[4-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)-6-METHYL-5-NITROPYRIMIDIN-2-YL]MORPHOLINE

IUPAC name

n/a

SMILES

Cc1cc(C)nn1-c(nc(N1CCOCC1)nc1C)c1[N+]([O-])=O

InChI

InChI=1S/C14H18N6O3/c1-9-8-10(2)19(17-9)13-12(20(21)22)11(3)15-14(16-13)18-4-6-23-7-5-18/h8H,4-7H2,1-3H3

InChI Key

HSRBLRQEBKXOLC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02995662

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

318.34

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.767

Distribution Coefficient, logD

1.767

Water Solubility, LogSw

-1.77

Polar Surface Area

76.259

Acid Dissociation Constant (pKa)

20.44

Base Dissociation Constant (pKb)

1.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.00

4290-0148 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 4290-0148 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4290-0148?
Check Price and Availability of 4290-0148, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4290-0148 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4290-0148
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4290-0148
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4290-0148 available by request