4358-1465 Screening compound: ethyl 6-methoxy-4-{[3-(methoxycarbonyl)phenyl]amino}quinoline-3-carboxylate

4358-1465 Screening compound: ethyl 6-methoxy-4-{[3-(methoxycarbonyl)phenyl]amino}quinoline-3-carboxylate
4358-1465 Screening compound: ethyl 6-methoxy-4-{[3-(methoxycarbonyl)phenyl]amino}quinoline-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound 4358-1465
ethyl 6-methoxy-4-{[3-(methoxycarbonyl)phenyl]amino}quinoline-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4358-1465

Molecular Formula

C21H20N2O5 (C21 H20 N2 O5)

Compound Name

ethyl 6-methoxy-4-{[3-(methoxycarbonyl)phenyl]amino}quinoline-3-carboxylate

IUPAC name

ethyl 6-methoxy-4-{[3-(methoxycarbonyl)phenyl]amino}quinoline-3-carboxylate

SMILES

CCOC(c(cnc(c1c2)ccc2OC)c1Nc1cc(C(OC)=O)ccc1)=O

InChI

InChI=1S/C21H20N2O5/c1-4-28-21(25)17-12-22-18-9-8-15(26-2)11-16(18)19(17)23-14-7-5-6-13(10-14)20(24)27-3/h5-12H,4H2,1-3H3,(H,22,23)

InChI Key

HGAPMJILNXBVOX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02363706

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.4

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.555

Distribution Coefficient, logD

4.554

Water Solubility, LogSw

-4.26

Polar Surface Area

66.079

Acid Dissociation Constant (pKa)

15.92

Base Dissociation Constant (pKb)

4.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

4358-1465 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 4358-1465 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4358-1465?
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What is the minimum amount of 4358-1465 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4358-1465
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4358-1465
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4358-1465 available by request