4386-0356 Screening compound: 5-chloro-2-(4-{4-[4-(5-chloro-1,3-dioxo-2,3,3a,4,7,7a-hexahydro-1H-isoindol-2-yl)butyl]piperazin-1-yl}butyl)-2,3,3a,4,7,7a-hexahydro-1H-isoindole-1,3-dione

4386-0356 Screening compound: 5-chloro-2-(4-{4-[4-(5-chloro-1,3-dioxo-2,3,3a,4,7,7a-hexahydro-1H-isoindol-2-yl)butyl]piperazin-1-yl}butyl)-2,3,3a,4,7,7a-hexahydro-1H-isoindole-1,3-dione
4386-0356 Screening compound: 5-chloro-2-(4-{4-[4-(5-chloro-1,3-dioxo-2,3,3a,4,7,7a-hexahydro-1H-isoindol-2-yl)butyl]piperazin-1-yl}butyl)-2,3,3a,4,7,7a-hexahydro-1H-isoindole-1,3-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound 4386-0356
5-chloro-2-(4-{4-[4-(5-chloro-1,3-dioxo-2,3,3a,4,7,7a-hexahydro-1H-isoindol-2-yl)butyl]piperazin-1-yl}butyl)-2,3,3a,4,7,7a-hexahydro-1H-isoindole-1,3-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4386-0356

Molecular Formula

C28H38Cl2N4O4 (C28 H38 Cl2 N4 O4)

Compound Name

5-chloro-2-(4-{4-[4-(5-chloro-1,3-dioxo-2,3,3a,4,7,7a-hexahydro-1H-isoindol-2-yl)butyl]piperazin-1-yl}butyl)-2,3,3a,4,7,7a-hexahydro-1H-isoindole-1,3-dione

IUPAC name

5-chloro-2-(4-{4-[4-(5-chloro-13-dioxo-233a477a-hexahydro-1H-isoindol-2-yl)butyl]piperazin-1-yl}butyl)-233a477a-hexahydro-1H-isoindole-13-dione

SMILES

O=C(C1C2CC(Cl)=CC1)N(CCCCN1CCN(CCCCN(C(C3C4CC(Cl)=CC3)=O)C4=O)CC1)C2=O

InChI

InChI=1S/C28H38Cl2N4O4/c29-19-5-7-21-23(17-19)27(37)33(25(21)35)11-3-1-9-31-13-15-32(16-14-31)10-2-4-12-34-26(36)22-8-6-20(30)18-24(22)28(34)38/h5-6,21-24H,1-4,7-18H2

InChI Key

RDYNLGDFVJMISN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14710027

Chemical and Physical Properties

Saltdata

2HCl

Molecular Weight

565.54

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.331

Distribution Coefficient, logD

0.659

Water Solubility, LogSw

-3.06

Polar Surface Area

66.858

Acid Dissociation Constant (pKa)

19.12

Base Dissociation Constant (pKb)

9.06

Number of Chiral Centers

4.00

Percent sp3 carbon bonding

71.40

4386-0356 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 4386-0356 chemical compound. It will be published here after verification.

Frequently Asked Questions

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What is the minimum amount of 4386-0356 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4386-0356
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4386-0356
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4386-0356 available by request