4485-0736 Screening compound: 4-(4-bromobenzoyl)-3-hydroxy-1,5-diphenyl-2,5-dihydro-1H-pyrrol-2-one

4485-0736 Screening compound: 4-(4-bromobenzoyl)-3-hydroxy-1,5-diphenyl-2,5-dihydro-1H-pyrrol-2-one
4485-0736 Screening compound: 4-(4-bromobenzoyl)-3-hydroxy-1,5-diphenyl-2,5-dihydro-1H-pyrrol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 4485-0736
4-(4-bromobenzoyl)-3-hydroxy-1,5-diphenyl-2,5-dihydro-1H-pyrrol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4485-0736

Molecular Formula

C23H16BrNO3 (C23 H16 BrNO3)

Compound Name

4-(4-bromobenzoyl)-3-hydroxy-1,5-diphenyl-2,5-dihydro-1H-pyrrol-2-one

IUPAC name

4-(4-bromobenzoyl)-3-hydroxy-15-diphenyl-25-dihydro-1H-pyrrol-2-one

SMILES

OC(C(N(C1c2ccccc2)c2ccccc2)=O)=C1C(c(cc1)ccc1Br)=O

InChI

InChI=1S/C23H16BrNO3/c24-17-13-11-16(12-14-17)21(26)19-20(15-7-3-1-4-8-15)25(23(28)22(19)27)18-9-5-2-6-10-18/h1-14,20,27H/t20-/m1/s1

InChI Key

FVKHOZHJJZLNMD-HXUWFJFHSA-N

MDL Number (MFCD)

MFCD01821687

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.29

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.754

Distribution Coefficient, logD

4.752

Water Solubility, LogSw

-4.74

Polar Surface Area

44.215

Acid Dissociation Constant (pKa)

9.95

Base Dissociation Constant (pKb)

-6.67

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

4.30

4485-0736 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with 4485-0736 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4485-0736?
Check Price and Availability of 4485-0736, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4485-0736 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4485-0736
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4485-0736
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4485-0736 available by request