4524-0145 Screening compound: 6-bromo-2-(2,5-dimethylphenyl)quinoline-4-carboxylic acid

4524-0145 Screening compound: 6-bromo-2-(2,5-dimethylphenyl)quinoline-4-carboxylic acid
4524-0145 Screening compound: 6-bromo-2-(2,5-dimethylphenyl)quinoline-4-carboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound 4524-0145
6-bromo-2-(2,5-dimethylphenyl)quinoline-4-carboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4524-0145

Molecular Formula

C18H14BrNO2 (C18 H14 BrNO2)

Compound Name

6-bromo-2-(2,5-dimethylphenyl)quinoline-4-carboxylic acid

IUPAC name

6-bromo-2-(25-dimethylphenyl)quinoline-4-carboxylic acid

SMILES

Cc1cc(-c2cc(C(O)=O)c(cc(cc3)Br)c3n2)c(C)cc1

InChI

InChI=1S/C18H14BrNO2/c1-10-3-4-11(2)13(7-10)17-9-15(18(21)22)14-8-12(19)5-6-16(14)20-17/h3-9H,1-2H3,(H,21,22)

InChI Key

TWFOBDCWQWVNLL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02602228

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

356.22

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

5.788

Distribution Coefficient, logD

0.905

Water Solubility, LogSw

-5.42

Polar Surface Area

36.706

Acid Dissociation Constant (pKa)

3.11

Base Dissociation Constant (pKb)

3.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

4524-0145 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Antiviral Library (67538 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • Epigenetic
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with 4524-0145 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4524-0145?
Check Price and Availability of 4524-0145, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4524-0145 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4524-0145
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4524-0145
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4524-0145 available by request