4618-0589 Screening compound: 4-methyl-N'-[(E)-[2-(morpholin-4-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl]methylidene]benzene-1-sulfonohydrazide

4618-0589 Screening compound: 4-methyl-N'-[(E)-[2-(morpholin-4-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl]methylidene]benzene-1-sulfonohydrazide
4618-0589 Screening compound: 4-methyl-N'-[(E)-[2-(morpholin-4-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl]methylidene]benzene-1-sulfonohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 4618-0589
4-methyl-N'-[(E)-[2-(morpholin-4-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl]methylidene]benzene-1-sulfonohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4618-0589

Molecular Formula

C20H21N5O4S (C20 H21 N5 O4 S)

Compound Name

4-methyl-N'-[(E)-[2-(morpholin-4-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl]methylidene]benzene-1-sulfonohydrazide

IUPAC name

4-methyl-N'-[(E)-[2-(morpholin-4-yl)-4-oxo-4H-pyrido[12-a]pyrimidin-3-yl]methylidene]benzene-1-sulfonohydrazide

SMILES

Cc(cc1)ccc1S(N/N=C/C1=C(N2CCOCC2)N=C(C=CC=C2)N2C1=O)(=O)=O

InChI

InChI=1S/C20H21N5O4S/c1-15-5-7-16(8-6-15)30(27,28)23-21-14-17-19(24-10-12-29-13-11-24)22-18-4-2-3-9-25(18)20(17)26/h2-9,14,23H,10-13H2,1H3

InChI Key

RSDAKUAWSNRIHQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01071961

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.48

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.617

Distribution Coefficient, logD

-0.729

Water Solubility, LogSw

-2.64

Polar Surface Area

87.530

Acid Dissociation Constant (pKa)

5.06

Base Dissociation Constant (pKb)

4.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

4618-0589 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with 4618-0589 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4618-0589?
Check Price and Availability of 4618-0589, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4618-0589 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4618-0589
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4618-0589
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4618-0589 available by request